{"id":"W2070317104","doi":"10.1158/0008-5472.can-03-0969","title":"p53 Activation in Chronic Radiation-Treated Breast Cancer Cells","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Atomic Energy of Canada Limited; City of Hope; Harvard University","keywords":"Radioresistance; Mdm2; Biology; DNA damage; Cancer research; MCF-7; Western blot; Molecular biology; Cancer cell; Cell culture; Cancer; DNA; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297795,0.0002577104,0.0003423386,0.0002574287,0.0002115287,0.0002779411,0.0001373681,0.0002387683,0.002416889],"category_scores_gemma":[0.00009862983,0.0001460946,0.0002608215,0.0003500958,0.0001492064,0.0001582416,0.0001726051,0.0005066833,0.0007059093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002320552,"about_ca_system_score_gemma":0.0001483131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000567542,"about_ca_topic_score_gemma":0.0006862784,"domain_scores_codex":[0.999806,0.00002407731,0.0000176945,0.00005383398,0.00005673387,0.00004174633],"domain_scores_gemma":[0.9999126,0.00001592278,0.00002008494,0.00001860884,0.00001851254,0.00001437834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001232847,0.0000298669,0.0003287106,0.00004037728,0.000004482186,0.0000634173,0.00001947096,0.00001690813,0.9983778,0.00002267227,0.00005113906,0.0009217972],"study_design_scores_gemma":[0.00002051494,0.0008989105,0.0230914,0.0000114162,0.0000232884,0.0007383511,0.00007458633,0.0003990792,0.9702691,0.00004598014,0.004421109,0.000006419887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883988,0.005470288,0.002815596,0.0001419861,0.00007273469,0.00005245612,0.001134165,0.0001057379,0.001808253],"genre_scores_gemma":[0.9850878,0.002743467,0.002336112,0.00013674,0.00004957433,0.0001591209,0.003538528,0.00001870066,0.005929971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002416889,"threshold_uncertainty_score":0.008085251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04175609784155685,"score_gpt":0.3863324564284015,"score_spread":0.3445763585868447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}