{"id":"W2070343571","doi":"10.1227/neu.0b013e318230ac63","title":"O-6-Methylguanine-DNA Methyltransferase (MGMT) Immunohistochemical Expression in Pituitary Corticotroph Adenomas","year":2011,"lang":"en","type":"article","venue":"Neurosurgery","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Jarislowsky Foundation","keywords":"Temozolomide; Corticotropic cell; Medicine; Cushing's disease; Pituitary adenoma; Immunohistochemistry; Adenoma; Pathology; Methyltransferase; Glioma; Internal medicine; Pituitary tumors; Oncology; Cancer research; Pituitary gland; Disease; Biology; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328064,0.0002855519,0.0005377675,0.0002948012,0.00005405657,0.00001115853,0.0001020795,0.0001430131,0.0004090976],"category_scores_gemma":[0.0001633811,0.0002411812,0.0002524327,0.0003104696,0.00009222756,0.0001071906,0.00004683245,0.0003189346,0.00009241918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009138392,"about_ca_system_score_gemma":0.00007434098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001051135,"about_ca_topic_score_gemma":0.000003721638,"domain_scores_codex":[0.9980867,0.0001004943,0.0005516485,0.0005029929,0.0003132498,0.0004449337],"domain_scores_gemma":[0.9988816,0.0002046802,0.00007426413,0.0005389837,0.00004832094,0.0002521385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005046788,0.001521207,0.1657066,0.00002975637,0.0000325957,0.003906975,0.0002384397,0.000001077518,0.8251862,0.00002541087,0.001348079,0.001499003],"study_design_scores_gemma":[0.001706349,0.0002554723,0.4031501,0.0001244756,0.0001035894,0.0001938018,0.00002921964,0.0000172525,0.5933822,0.00006787005,0.0007709201,0.0001987837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957407,0.00134891,0.00002609921,0.000224182,0.0004428164,0.0004021286,0.000009695463,0.0001040641,0.001701434],"genre_scores_gemma":[0.9979261,0.0003572377,0.000729273,0.0006273433,0.00007684322,0.00013834,0.00002984064,0.00005560911,0.00005948008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2374435,"threshold_uncertainty_score":0.9835085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03322837471343501,"score_gpt":0.2543926634184533,"score_spread":0.2211642887050183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}