{"id":"W2070371849","doi":"10.1074/jbc.m111.302596","title":"Efnb1 and Efnb2 Proteins Regulate Thymocyte Development, Peripheral T Cell Differentiation, and Antiviral Immune Responses and Are Essential for Interleukin-6 (IL-6) Signaling","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Institut National de la Recherche Scientifique; Hôpital Notre-Dame","funders":"Natural Science Foundation of Zhejiang Province; Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Heart and Stroke Foundation of Canada; Ministero dello Sviluppo Economico; National Natural Science Foundation of China","keywords":"Biology; Erythropoietin-producing hepatocellular (Eph) receptor; Ephrin; Cell biology; Kinase; T cell; Thymocyte; CD8; Immune system; Receptor tyrosine kinase; Signal transduction; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000298474,0.000183992,0.000302537,0.00003143541,0.0002035337,0.00006410483,0.000180743,0.0001230708,0.00002741673],"category_scores_gemma":[0.0004221529,0.0001300623,0.00006775137,0.0000534535,0.000225128,0.000144928,0.0001499179,0.0002271725,2.549365e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001848554,"about_ca_system_score_gemma":0.00003582942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.816547e-7,"about_ca_topic_score_gemma":2.229111e-7,"domain_scores_codex":[0.99876,0.00007743715,0.000506695,0.0002960473,0.0001325944,0.0002272459],"domain_scores_gemma":[0.9990435,0.0001877996,0.0005130883,0.00008630316,0.00006744099,0.0001018284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001065485,0.00006298509,0.005430808,0.00007998553,0.000009957653,0.00003446102,0.000253885,3.195302e-7,0.9924182,0.000005757204,0.000005241595,0.0006329359],"study_design_scores_gemma":[0.0008216304,0.0002411041,0.01510727,0.0001081794,0.0000156457,0.0001800301,0.0001181788,0.00003709677,0.9826877,0.0003509084,0.0001653431,0.0001668863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99849,0.0005659792,0.0006318371,0.0000598646,0.00004923431,0.0001317074,0.000009305752,0.00001374373,0.00004829073],"genre_scores_gemma":[0.9979571,0.0002453505,0.001491456,0.00007099952,0.0001129425,0.000006601893,0.000001088165,0.00001090118,0.0001035787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009730455,"threshold_uncertainty_score":0.5303787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05135371218226224,"score_gpt":0.2528692142426736,"score_spread":0.2015155020604114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}