{"id":"W2070371849","doi":"10.1074/jbc.m111.302596","title":"Efnb1 and Efnb2 Proteins Regulate Thymocyte Development, Peripheral T Cell Differentiation, and Antiviral Immune Responses and Are Essential for Interleukin-6 (IL-6) Signaling","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Institut National de la Recherche Scientifique; Hôpital Notre-Dame","funders":"Natural Science Foundation of Zhejiang Province; Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Heart and Stroke Foundation of Canada; Ministero dello Sviluppo Economico; National Natural Science Foundation of China","keywords":"Biology; Erythropoietin-producing hepatocellular (Eph) receptor; Ephrin; Cell biology; Kinase; T cell; Thymocyte; CD8; Immune system; Receptor tyrosine kinase; Signal transduction; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008815485,0.0003414495,0.0001651319,0.0001944446,0.0002014733,0.0002695454,0.0001602166,0.0002431858,0.001277481],"category_scores_gemma":[0.00007376657,0.00009832736,0.0001252344,0.00008881409,0.0002015534,0.0002385151,0.0002182662,0.0003334164,0.0003265232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000219906,"about_ca_system_score_gemma":0.0001346398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003497871,"about_ca_topic_score_gemma":0.0005184421,"domain_scores_codex":[0.9998826,0.00001185719,0.000008970938,0.00003470184,0.00002837191,0.00003349174],"domain_scores_gemma":[0.9999337,0.000004000638,0.00002527223,0.000005264716,0.000008009006,0.00002379914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008492923,0.000007876471,0.0006790267,0.00002611182,0.000002454237,0.00007387481,0.00001262375,0.00004202382,0.9972908,0.0001719267,0.00003979467,0.001568581],"study_design_scores_gemma":[0.0000352529,0.000136752,0.04052415,0.00002221225,0.00002754247,0.001657567,0.0001175331,0.001634271,0.9407483,0.0002955742,0.014789,0.00001183799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867655,0.004720841,0.005206622,0.00009486824,0.00003362798,0.00001616374,0.0005814627,0.0000819083,0.002498911],"genre_scores_gemma":[0.9932508,0.001006404,0.001452223,0.00002898104,0.0000110279,0.00001945075,0.0004120916,0.00001649623,0.003802589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277481,"threshold_uncertainty_score":0.004273593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05135371218226224,"score_gpt":0.2528692142426736,"score_spread":0.2015155020604114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}