{"id":"W2070416230","doi":"10.1016/j.stem.2009.02.010","title":"Alternative Induced Pluripotent Stem Cell Characterization Criteria for In Vitro Applications","year":2009,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; SickKids Foundation; University of Toronto","funders":"","keywords":"Biology; Induced pluripotent stem cell; Cell biology; In vitro; Stem cell; Computational biology; Embryonic stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003351432,0.0007734582,0.000697124,0.0003674948,0.000162151,0.0001657836,0.001094075,0.001497401,0.00002832515],"category_scores_gemma":[0.000002670597,0.0008356692,0.0003605659,0.000271926,0.00006609079,0.00001680026,0.0002908089,0.001048361,0.0001415111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002379479,"about_ca_system_score_gemma":0.0002636014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002955457,"about_ca_topic_score_gemma":0.000004058395,"domain_scores_codex":[0.9955415,0.0003376325,0.0008743265,0.001609668,0.0005495095,0.001087401],"domain_scores_gemma":[0.997645,0.00006955755,0.0006015512,0.001178367,0.0003219951,0.0001835779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001546961,0.0002495468,0.000006664816,0.0009102694,0.00002714685,0.00004381434,0.00006989118,0.00001507452,0.956045,6.450402e-7,0.03882922,0.003648078],"study_design_scores_gemma":[0.0008916374,0.0002096774,0.00001173949,0.00003094405,0.0000327521,0.000003667611,0.00003084292,0.0001872324,0.5865535,0.00001078911,0.4115273,0.0005099244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7251143,0.008007524,0.0913028,0.07725367,0.004958828,0.0434484,0.009810579,0.0004543772,0.03964954],"genre_scores_gemma":[0.6685786,0.002383521,0.001484362,0.1116641,0.01273672,0.006638515,0.05941857,0.000955517,0.1361401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3726981,"threshold_uncertainty_score":0.9997989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345940598239571,"score_gpt":0.2708464179698374,"score_spread":0.2473870119874417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}