{"id":"W2070423225","doi":"10.1021/ol9021904","title":"Stereospecific Synthesis of α-Substituted <i>syn</i>-α,β-Diamino Acids by the Diaza-Cope Rearrangement","year":2009,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Stereospecificity; Chemistry; Cope rearrangement; Ketone; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001669482,0.0002183635,0.0002732711,0.00003563302,0.0001376744,0.00005600603,0.0004952815,0.000087476,0.002496589],"category_scores_gemma":[0.0001060632,0.0001606128,0.0001437503,0.0002075665,0.0001192367,0.0001049236,0.00003387178,0.0001777662,0.0001440399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001234222,"about_ca_system_score_gemma":0.00002960111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000380465,"about_ca_topic_score_gemma":0.0000041022,"domain_scores_codex":[0.9986333,0.00002417595,0.0003642956,0.000314019,0.0003579866,0.0003061969],"domain_scores_gemma":[0.9986488,0.0002262467,0.0001752689,0.000841364,0.00003212825,0.00007625546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001277638,0.0001019202,0.0002637428,0.00001683203,0.00007834915,0.000005096449,0.0001508738,7.352261e-7,0.9514519,0.00004390898,0.03519609,0.01267778],"study_design_scores_gemma":[0.0002205637,0.000007471824,0.001797147,0.00005019035,0.000118962,0.00001546565,0.0002791564,0.000005640891,0.9668685,0.00001340242,0.03042442,0.0001990857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763568,0.0002862192,0.0001797679,0.01118296,0.0001475207,0.0001120755,0.00005659263,0.00009357531,0.01158449],"genre_scores_gemma":[0.998085,0.0001133332,0.00007070803,0.001067413,0.0001642282,0.0000215457,0.00002398738,0.00002899941,0.0004248354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02172815,"threshold_uncertainty_score":0.9984153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0093182589387947,"score_gpt":0.1991015254397976,"score_spread":0.1897832665010029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}