{"id":"W2070424067","doi":"10.1089/153685903321948021","title":"Development of Functional Human Monoclonal Single-Chain Variable Fragment Antibody Against HIV-1 from Human Cervical B Cells","year":2003,"lang":"en","type":"article","venue":"Hybridoma and Hybridomics","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Canadian Science Centre for Human and Animal Health","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Monoclonal antibody; Virology; Biology; Epitope; Antibody; Phage display; Recombinant DNA; Molecular biology; Single-chain variable fragment; clone (Java method); Immunoglobulin light chain; Flow cytometry; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004702639,0.0004026598,0.0007531495,0.0002100643,0.0004925958,0.00005715781,0.0001579918,0.0001260935,0.0009459591],"category_scores_gemma":[0.00004029759,0.0003665586,0.0001787853,0.0001802638,0.0002936921,0.00009336363,0.0001669074,0.0004219308,0.00006906733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001307133,"about_ca_system_score_gemma":0.000295682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009574661,"about_ca_topic_score_gemma":0.00001558716,"domain_scores_codex":[0.9969761,0.0001018352,0.0009071352,0.0006468774,0.0007564749,0.000611557],"domain_scores_gemma":[0.998602,0.0001658097,0.0002023162,0.0003739764,0.0001984355,0.0004574788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005302638,0.001116599,0.01235521,0.0002323733,0.0003833679,0.0001579957,0.0002352747,0.00004946176,0.9713988,0.009800932,0.002516477,0.001223215],"study_design_scores_gemma":[0.01239389,0.0008047487,0.07115374,0.000650444,0.0003295777,0.0003657431,0.0005636569,0.001654048,0.6531779,0.00424167,0.2531876,0.001476981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986955,0.0004652459,0.002350723,0.0001583958,0.0002308135,0.0004043537,0.0002006313,0.00004624614,0.00918863],"genre_scores_gemma":[0.9706402,0.00008555908,0.02423808,0.0004884082,0.000358489,0.00002385781,0.001417375,0.00005910076,0.002688885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3182209,"threshold_uncertainty_score":0.9999673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0366388263447839,"score_gpt":0.27973413632361,"score_spread":0.2430953099788261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}