{"id":"W2070522618","doi":"10.1158/1078-0432.ccr-12-1397","title":"Serum Lactate Dehydrogenase Is Prognostic for Survival in Patients with Bone Metastases from Breast Cancer: A Retrospective Analysis in Bisphosphonate-Treated Patients","year":2012,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Cancer Research UK; Novartis Pharmaceuticals Corporation","keywords":"Medicine; Lactate dehydrogenase; Internal medicine; Breast cancer; Proportional hazards model; Zoledronic acid; Cancer; Chemotherapy; Oncology; Relative risk; Gastroenterology; Retrospective cohort study; Urology; Surgery; Confidence interval; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006662431,0.0002256759,0.0004256104,0.0004731261,0.0002332861,0.0004439235,0.0002635696,0.0003003325,0.0007990245],"category_scores_gemma":[0.00161017,0.0002344267,0.0006169904,0.0006351761,0.0002797796,0.0002303674,0.0002297511,0.0003898415,0.0001647783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002632772,"about_ca_system_score_gemma":0.0002892494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454227,"about_ca_topic_score_gemma":0.001289621,"domain_scores_codex":[0.9995793,0.000129604,0.00005843251,0.00009689399,0.00008795255,0.000047936],"domain_scores_gemma":[0.9988428,0.0002895826,0.0005121373,0.0001084823,0.00008750547,0.0001593784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004687379,0.00001522953,0.9985088,0.000006652246,0.00009600291,0.00004479524,0.000009651917,0.00004808881,0.0002150518,0.000004295037,0.00002834809,0.0005543975],"study_design_scores_gemma":[0.00003416142,0.0003382353,0.9980314,0.000005036917,0.0001169196,0.0006204235,0.00004197557,0.0004528975,0.0001606969,0.00001766332,0.0001761805,0.000004239095],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991249,0.0004942396,0.00009624565,0.00001665084,0.000003612148,0.000004158449,0.0001777227,0.000002540952,0.00007986779],"genre_scores_gemma":[0.9995652,0.0000979713,0.00004819141,0.000009552986,0.000005857114,0.000004688239,0.0002373762,7.779194e-7,0.00003044399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001454227,"threshold_uncertainty_score":0.003523469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08758147656428107,"score_gpt":0.4566996469113921,"score_spread":0.369118170347111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}