{"id":"W2070615987","doi":"10.1016/j.ijrobp.2010.07.103","title":"Initial Report of RTOG 9601: A Phase III Trial in Prostate Cancer: Anti-androgen Therapy (AAT) with Bicalutamide during and after Radiation Therapy (RT) Improves Freedom from Progression and Reduces the Incidence of Metastatic Disease in Patients following Radical Prostatectomy (RP) with pT2-3, N0 Disease, and Elevated PSA Levels","year":2010,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Bicalutamide; Prostate cancer; Urology; Clinical endpoint; Androgen deprivation therapy; Radiation therapy; Randomized controlled trial; Incidence (geometry); Prostate-specific antigen; Internal medicine; Placebo; Prostate; Cancer; Oncology; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004993205,0.002213612,0.002375253,0.0004410601,0.0006970422,0.001531664,0.001354261,0.003158747,0.004208622],"category_scores_gemma":[0.003809102,0.000621516,0.002242744,0.00058549,0.0009802604,0.0008413449,0.0004551323,0.00644489,0.001800465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001217448,"about_ca_system_score_gemma":0.002586682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001959242,"about_ca_topic_score_gemma":0.004441408,"domain_scores_codex":[0.9990278,0.0004676737,0.00007629926,0.0001256454,0.0001375132,0.0001649119],"domain_scores_gemma":[0.9970619,0.001102667,0.0003152349,0.0001604986,0.0002207187,0.001139014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.599975,0.03748182,0.01406975,0.002088682,0.005822267,0.002424567,0.0007030446,0.006515533,0.04886347,0.001183964,0.06660563,0.2142663],"study_design_scores_gemma":[0.6571922,0.2679558,0.02317282,0.0001540262,0.002380652,0.001212213,0.00009601491,0.002199633,0.01286727,0.000726568,0.03191143,0.0001314011],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9273878,0.01105578,0.003256404,0.01796127,0.002125847,0.006036889,0.0179425,0.0007093554,0.01352416],"genre_scores_gemma":[0.9082508,0.009210749,0.006931578,0.02137112,0.002298981,0.006821967,0.02480827,0.0002734551,0.0200331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004993205,"threshold_uncertainty_score":0.02640688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01710896266047948,"score_gpt":0.3618060771811993,"score_spread":0.3446971145207199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}