{"id":"W2070647652","doi":"10.1038/sj.embor.7400509","title":"TRBP, a regulator of cellular PKR and HIV‐1 virus expression, interacts with Dicer and functions in RNA silencing","year":2005,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":645,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Dicer; Argonaute; Biology; Small interfering RNA; RNA silencing; RNA interference; Gene silencing; RNA-induced silencing complex; Cell biology; RNA; Effector; Drosha; microRNA; Trans-acting siRNA; RNA-binding protein; Protein kinase R; Molecular biology; Genetics; Protein kinase A; Kinase; Gene; Mitogen-activated protein kinase kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000491145,0.0007232302,0.0008317675,0.0006093589,0.0009750206,0.001208498,0.0008079784,0.000804325,0.002263002],"category_scores_gemma":[0.0005509713,0.0005845242,0.0006738475,0.0003942836,0.0005569325,0.0008635025,0.0007092583,0.001213779,0.002788669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009311807,"about_ca_system_score_gemma":0.0004505446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008503027,"about_ca_topic_score_gemma":0.0009625449,"domain_scores_codex":[0.9994979,0.0000645307,0.00004213919,0.0001399177,0.0001429215,0.0001124425],"domain_scores_gemma":[0.9996374,0.00004509294,0.00009641347,0.00005451097,0.00005871914,0.0001078496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001539589,0.00001572113,0.0002234314,0.00005032293,0.00000924403,0.0002551494,0.00001508818,0.00008090497,0.996666,0.0003625243,0.0001929555,0.001974633],"study_design_scores_gemma":[0.00003195127,0.0001138666,0.004517964,0.00000796082,0.00002594058,0.002153929,0.00004294915,0.001766168,0.9862469,0.000253866,0.004823102,0.00001520379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9400269,0.01527841,0.03227591,0.0009134119,0.0002139135,0.00008564102,0.001063221,0.001032598,0.009110074],"genre_scores_gemma":[0.9704746,0.002889794,0.01368686,0.0001925742,0.00007095823,0.00005278683,0.001809268,0.0001770649,0.01064614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002263002,"threshold_uncertainty_score":0.007570505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004464534265583088,"score_gpt":0.2117625235150699,"score_spread":0.2072979892494868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}