{"id":"W2070667288","doi":"10.1261/rna.2910105","title":"Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase","year":2005,"lang":"en","type":"article","venue":"RNA","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Telomere; Telomerase; Telomerase reverse transcriptase; Reverse transcriptase; RNA; DNA; Transcription (linguistics); Nucleotide; Telomerase RNA component; Molecular biology; Mutant; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001859201,0.0001050984,0.0002610205,0.0001251807,0.00005179402,0.000006338503,0.0000443539,0.00006634738,0.0001076783],"category_scores_gemma":[0.00003844481,0.00009612753,0.00003775883,0.0001645766,0.0001236464,0.0001630959,0.00001889586,0.00007512087,0.000006728089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002447736,"about_ca_system_score_gemma":0.00002658981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001296133,"about_ca_topic_score_gemma":0.00003962456,"domain_scores_codex":[0.9991025,0.00002805592,0.0003761406,0.0001675484,0.00021015,0.0001156612],"domain_scores_gemma":[0.9993649,0.00003335438,0.0002349422,0.0001889362,0.00009854154,0.00007936935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008533756,0.0001129362,0.0166434,0.0001398639,0.00002187385,0.000002842159,0.0003537394,0.000009155337,0.9329805,0.0002368402,0.001151526,0.04826203],"study_design_scores_gemma":[0.001294367,0.0002890991,0.2578886,0.0002202067,0.00007261727,0.00001844901,0.00008601938,0.000649568,0.7363161,0.0002948158,0.002720867,0.0001492101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974328,0.0003288839,0.0001054242,0.0002936133,0.00002669456,0.0001908245,0.0000181607,0.00002768553,0.001575916],"genre_scores_gemma":[0.997538,0.0000950738,0.001456624,0.0000838284,0.00007042418,0.000002462957,0.00005115114,0.00001465663,0.0006878217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2412452,"threshold_uncertainty_score":0.3919967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01367641888291215,"score_gpt":0.2659634271071999,"score_spread":0.2522870082242877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}