{"id":"W2070667288","doi":"10.1261/rna.2910105","title":"Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase","year":2005,"lang":"en","type":"article","venue":"RNA","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Telomere; Telomerase; Telomerase reverse transcriptase; Reverse transcriptase; RNA; DNA; Transcription (linguistics); Nucleotide; Telomerase RNA component; Molecular biology; Mutant; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002023697,0.000272088,0.0002065479,0.0001532707,0.0001204903,0.0005280849,0.0002278649,0.0002054932,0.0005151631],"category_scores_gemma":[0.0002755438,0.0001872751,0.0001842163,0.0001167695,0.0002066468,0.0001697833,0.0002041776,0.0003445565,0.0002512366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000369033,"about_ca_system_score_gemma":0.0001470727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000644276,"about_ca_topic_score_gemma":0.0009250988,"domain_scores_codex":[0.999637,0.00006059167,0.00003644695,0.00009636839,0.0001262249,0.00004336367],"domain_scores_gemma":[0.9998316,0.00004594781,0.00005218564,0.00002555186,0.0000168654,0.00002783685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004460655,0.00001106006,0.0002455676,0.00001076575,0.000002042555,0.00002140846,0.00001209389,0.00006732845,0.9985895,0.00007105973,0.00001082006,0.0009137765],"study_design_scores_gemma":[0.00000595473,0.00007205048,0.002842876,0.000002480549,0.000003697009,0.0001170821,0.00001080999,0.00101999,0.9951137,0.00002562696,0.0007821946,0.000003638877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956117,0.001325681,0.001901608,0.00002828037,0.0000112341,0.00001586604,0.0001590116,0.00007329462,0.0008733186],"genre_scores_gemma":[0.9965565,0.0004594357,0.00183819,0.00001691436,0.000004617008,0.00001378851,0.0003466673,0.00002233147,0.0007415509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000644276,"threshold_uncertainty_score":0.0026775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01367641888291215,"score_gpt":0.2659634271071999,"score_spread":0.2522870082242877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}