{"id":"W2070676169","doi":"10.1074/jbc.m110.121749","title":"Nuclear-delimited Angiotensin Receptor-mediated Signaling Regulates Cardiomyocyte Gene Expression","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; McGill University; Université de Montréal","funders":"Canadian Institutes of Health Research; Fondation Leducq","keywords":"Angiotensin II; Nuclear transport; Receptor; Endoplasmic reticulum; Gene expression; Cell biology; Nuclear protein; Nuclear membrane; Molecular biology; Biology; Signal transduction; Cell nucleus; Chemistry; Internal medicine; Endocrinology; Nucleus; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008553724,0.0002403583,0.0001830712,0.00007667496,0.00008413641,0.0002701552,0.00008477538,0.0001225344,0.001444977],"category_scores_gemma":[0.00005760499,0.0000868289,0.0001471397,0.00007066291,0.0001386786,0.0001291485,0.0001185787,0.0003400782,0.0004471556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960721,"about_ca_system_score_gemma":0.0001417074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002887429,"about_ca_topic_score_gemma":0.0006784743,"domain_scores_codex":[0.9998916,0.00001751342,0.000005015106,0.00003229264,0.00002794844,0.00002569653],"domain_scores_gemma":[0.9999454,0.000009241539,0.00001278811,0.000005967504,0.000007993449,0.00001863822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002658935,0.00000362305,0.0001004764,0.00001349628,0.000001208528,0.00001574122,0.00000593545,0.000006319319,0.9992908,0.00003375883,0.000007400508,0.0004947173],"study_design_scores_gemma":[0.00001806761,0.0002564226,0.0240618,0.00001204786,0.00001883636,0.0004190081,0.00006261295,0.0006593339,0.9715514,0.00007332226,0.002861492,0.000005568961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873556,0.004388991,0.004240274,0.00009632902,0.00004641538,0.00001385162,0.0002525391,0.00007156708,0.003534472],"genre_scores_gemma":[0.9933619,0.001401284,0.001850809,0.00004235333,0.00001647341,0.00001205464,0.000235892,0.0000151969,0.003064067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001444977,"threshold_uncertainty_score":0.004833877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01488038894654205,"score_gpt":0.2472711248004187,"score_spread":0.2323907358538766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}