{"id":"W2070730813","doi":"10.3816/clc.2011.n.004","title":"Randomized Phase II Trial of Concurrent Versus Sequential Bortezomib Plus Docetaxel in Advanced Non–Small-Cell Lung Cancer: A California Cancer Consortium Trial","year":2011,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Cancer Institute; Takeda Oncology; Genentech; Eli Lilly and Company","keywords":"Medicine; Docetaxel; Lung cancer; Oncology; Randomized controlled trial; Internal medicine; Cancer; Bortezomib; Clinical trial; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002126069,0.002242876,0.003411451,0.0004029909,0.0007673143,0.001689647,0.001485917,0.001593182,0.008534214],"category_scores_gemma":[0.00197159,0.0009480191,0.00214782,0.0005640271,0.002061338,0.001267112,0.0006311306,0.004951346,0.001527332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002285927,"about_ca_system_score_gemma":0.00289319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007183044,"about_ca_topic_score_gemma":0.01570806,"domain_scores_codex":[0.999095,0.0004240691,0.00003284682,0.0002534172,0.00005223768,0.0001423723],"domain_scores_gemma":[0.9985381,0.0003022728,0.0002487954,0.0001675311,0.00007349694,0.0006698693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9813855,0.004267281,0.0006350988,0.0002525751,0.0008328428,0.00002032528,0.00004477454,0.000771104,0.001277293,0.0001240615,0.001651641,0.008737595],"study_design_scores_gemma":[0.9705969,0.02641164,0.00131781,0.00001531762,0.0003579482,0.00001796958,0.00002087058,0.0003132252,0.0001386055,0.0001285645,0.0006680115,0.00001313898],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818943,0.004168897,0.0006542541,0.001853836,0.001129055,0.003360312,0.002433462,0.0001778162,0.004328017],"genre_scores_gemma":[0.9806651,0.002202393,0.001584778,0.001929497,0.0005619491,0.00320483,0.002445629,0.00005941298,0.007346347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008534214,"threshold_uncertainty_score":0.02854979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0712764897375286,"score_gpt":0.4051115447035378,"score_spread":0.3338350549660092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}