{"id":"W2070750835","doi":"10.1074/jbc.m114.578708","title":"A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis without Affecting Longevity in Drosophila","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Longevity; Cell biology; Homeostasis; Drosophila (subgenus); Biology; Drosophila melanogaster; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000068334,0.0002894433,0.0001260853,0.0003497376,0.0001813238,0.0001983405,0.0001757829,0.0002331265,0.0009183397],"category_scores_gemma":[0.00008663553,0.0001437221,0.0001541639,0.00009787739,0.0002523703,0.0001344064,0.0002213539,0.000410614,0.0001660188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003707929,"about_ca_system_score_gemma":0.0001895977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087236,"about_ca_topic_score_gemma":0.00254003,"domain_scores_codex":[0.9999318,0.00001135281,0.00001017293,0.00001903778,0.00001387969,0.00001377377],"domain_scores_gemma":[0.9998435,0.00003706745,0.0000536886,0.00001927369,0.000009341627,0.00003716702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004648819,0.00001064984,0.0002402644,0.00002148714,0.000003143439,0.00004559155,0.00001629183,0.00009683889,0.9984205,0.0001118947,0.00001703129,0.0009697998],"study_design_scores_gemma":[0.00002578133,0.0003069869,0.01628454,0.0000141852,0.00002555797,0.0002733261,0.00006282869,0.001939277,0.9781277,0.00015355,0.002775437,0.00001082353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969169,0.0008015285,0.001072748,0.00004576657,0.00001250187,0.00001383886,0.0003422409,0.00005202944,0.000742499],"genre_scores_gemma":[0.9955838,0.0006647404,0.001582616,0.00006060449,0.00000525815,0.00003006094,0.0002970257,0.00002954317,0.001746274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001087236,"threshold_uncertainty_score":0.003072143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01436392298005301,"score_gpt":0.2635864405812006,"score_spread":0.2492225176011476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}