{"id":"W2070910058","doi":"10.1038/sj.gene.6364247","title":"Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5","year":2005,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Biology; CCL5; Allele; Chemokine receptor; HEK 293 cells; Amino acid; Chemotaxis; Chemokine receptor CCR5; Mutant; C-C chemokine receptor type 6; Mutation; Phenotype; V3 loop; Chemokine; Receptor; Genetics; Molecular biology; Virology; Peptide sequence; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002276249,0.0001241071,0.0001992801,0.00008896018,0.0004156066,0.00001648227,0.00005577079,0.0001000154,0.0002469956],"category_scores_gemma":[0.0002747353,0.0001011949,0.00003946547,0.00009249824,0.0001119999,0.00006932691,0.00009723786,0.000109958,0.00006132644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002358526,"about_ca_system_score_gemma":0.00007142938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002265529,"about_ca_topic_score_gemma":0.0002893155,"domain_scores_codex":[0.9992258,0.0001683434,0.0001597999,0.0001865738,0.00002997692,0.0002294981],"domain_scores_gemma":[0.9992577,0.0002496959,0.00005777812,0.0001778159,0.0002046144,0.0000523352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006173665,0.001377712,0.5769965,0.0002009632,0.001271406,0.000004726172,0.00159485,0.000025195,0.2644897,0.0006026676,0.02168349,0.1255792],"study_design_scores_gemma":[0.0018674,0.0004965694,0.9080273,0.00002487656,0.00004351226,0.00005963829,0.0002367708,0.000007953057,0.01207209,0.00005121965,0.07699621,0.0001164446],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935638,0.003577215,0.0005781499,0.001083837,0.0000978809,0.0003078533,0.0006236589,0.00001656082,0.0001509844],"genre_scores_gemma":[0.9963419,0.0003883367,0.0001751532,0.00004539585,0.00004126354,0.00006029401,0.0002463298,0.000008342634,0.002692949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3310308,"threshold_uncertainty_score":0.412661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02945666717557507,"score_gpt":0.2817692640719386,"score_spread":0.2523125968963635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}