{"id":"W2070910058","doi":"10.1038/sj.gene.6364247","title":"Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5","year":2005,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Biology; CCL5; Allele; Chemokine receptor; HEK 293 cells; Amino acid; Chemotaxis; Chemokine receptor CCR5; Mutant; C-C chemokine receptor type 6; Mutation; Phenotype; V3 loop; Chemokine; Receptor; Genetics; Molecular biology; Virology; Peptide sequence; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002430938,0.0004845044,0.0003075254,0.000285947,0.000269316,0.0006933156,0.000370813,0.0003725755,0.002413147],"category_scores_gemma":[0.0003859976,0.0001466753,0.0003916158,0.000198933,0.0004560883,0.0002711042,0.00031928,0.000957158,0.0005419793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005158672,"about_ca_system_score_gemma":0.000171487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002112757,"about_ca_topic_score_gemma":0.002794555,"domain_scores_codex":[0.9995239,0.00009581455,0.00004029438,0.0000449416,0.000103492,0.0001915387],"domain_scores_gemma":[0.9996774,0.0000753398,0.0000653006,0.00005232689,0.00002924816,0.0001004835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000200938,0.00003607932,0.0002657795,0.00002088358,0.000009227557,0.00006462249,0.00002828208,0.00007985096,0.9981401,0.000373999,0.00007717817,0.0007030075],"study_design_scores_gemma":[0.00004379443,0.0006567508,0.01001565,0.00001365807,0.00004411119,0.001222999,0.0001737505,0.001655285,0.9827116,0.0002013438,0.003227172,0.00003389999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956132,0.000803745,0.001430033,0.00008202415,0.00004950079,0.00002862753,0.0004038117,0.00005591139,0.001533236],"genre_scores_gemma":[0.9960817,0.0002124299,0.001234362,0.0001006062,0.00001419949,0.00002228609,0.0008700286,0.00003529804,0.001429197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002413147,"threshold_uncertainty_score":0.008072793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02945666717557507,"score_gpt":0.2817692640719386,"score_spread":0.2523125968963635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}