{"id":"W2070972040","doi":"10.1016/j.jim.2013.11.017","title":"Development and validation of a lateral flow assay (LFA) for the determination of IgG-antibodies to Pr3 (cANCA) and MPO (pANCA)","year":2013,"lang":"en","type":"review","venue":"Journal of Immunological Methods","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Panca; Medicine; Myeloperoxidase; Autoantibody; Proteinase 3; Antibody; Immunology; Granulomatosis with polyangiitis; Microscopic polyangiitis; Pathology; Anti-neutrophil cytoplasmic antibody; Intensive care medicine; Vasculitis; Disease; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002196781,0.0001944359,0.001405768,0.0002191475,0.00008046594,0.00002443729,0.0001302593,0.0003092343,0.00002783405],"category_scores_gemma":[0.001182346,0.00009334582,0.0003192677,0.0001439787,0.0001187183,0.00006882849,0.0000770812,0.0003761285,5.225307e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005270222,"about_ca_system_score_gemma":0.0001308291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001842693,"about_ca_topic_score_gemma":2.563552e-7,"domain_scores_codex":[0.9979808,0.0004518213,0.001086992,0.000139428,0.0002049032,0.0001360329],"domain_scores_gemma":[0.9971697,0.001247699,0.0009810551,0.0001384226,0.0004008151,0.00006230442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003819684,0.00005411244,0.00001530408,0.001829904,0.0005789126,0.000003013339,0.0001729223,4.063369e-7,0.0004979023,0.00008276395,0.00002704786,0.9966995],"study_design_scores_gemma":[0.002709947,0.003311613,0.006746686,0.03107902,0.007247882,0.001981642,0.0002793468,0.000137951,0.005606572,0.001293206,0.9391147,0.0004913918],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004779656,0.9475825,0.04615011,0.0002517649,0.0002344409,0.0009484895,0.0000137438,0.000004583988,0.00003464491],"genre_scores_gemma":[0.00008141289,0.5809596,0.418781,0.00001114524,0.00004076297,0.00003692159,0.000007489904,0.000008769318,0.00007295839],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9962081,"threshold_uncertainty_score":0.3806532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1158492229950459,"score_gpt":0.4325728050099713,"score_spread":0.3167235820149253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}