{"id":"W2070998855","doi":"10.1038/leu.2013.73","title":"The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia","year":2013,"lang":"en","type":"article","venue":"Leukemia","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; Conquer Cancer Foundation; National Institutes of Health; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; U.S. Public Health Service; Canada Research Chairs","keywords":"EIF4E; Myeloid leukemia; Biology; Cancer research; Eukaryotic translation; Haematopoiesis; Translation (biology); Oncogene; Enhancer; Promoter; Myeloid; Molecular biology; Transcription factor; Messenger RNA; Genetics; Gene expression; Cell; Gene; Stem cell; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002162688,0.0003193896,0.000280859,0.0005678331,0.0003012634,0.000450375,0.0001995104,0.0002664482,0.000992703],"category_scores_gemma":[0.0002700277,0.0002188288,0.0001863364,0.0004347241,0.0003113458,0.00023691,0.0002859808,0.0004051109,0.0003822828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00039817,"about_ca_system_score_gemma":0.0002000447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003179462,"about_ca_topic_score_gemma":0.0004522133,"domain_scores_codex":[0.9997107,0.00003107301,0.00002842203,0.00004252515,0.0001049259,0.00008236015],"domain_scores_gemma":[0.9998307,0.00001278825,0.00008040471,0.00001379093,0.00002148398,0.00004079557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006692475,0.00002997992,0.006387549,0.00005913452,0.00002211234,0.0005019684,0.0000229435,0.00006651748,0.9884083,0.000159431,0.0002136587,0.003459113],"study_design_scores_gemma":[0.0001340448,0.0002980629,0.1675192,0.00002055436,0.0001116457,0.006276972,0.0002533673,0.00161452,0.8093352,0.0006939103,0.01372645,0.00001607775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922734,0.004374872,0.001767835,0.0001800528,0.00007662927,0.00001211503,0.0004027293,0.00007405083,0.000838314],"genre_scores_gemma":[0.9970075,0.0008840239,0.0006088333,0.00003965753,0.00002533666,0.00001134614,0.0004372006,0.00001123606,0.000974835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000992703,"threshold_uncertainty_score":0.003320992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205335706463775,"score_gpt":0.2112691652381853,"score_spread":0.1992158081735475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}