{"id":"W2071006115","doi":"10.1182/blood-2012-02-412593","title":"MHC I–associated peptides preferentially derive from transcripts bearing miRNA response elements","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Pfizer","keywords":"Biology; Transcriptome; microRNA; Biogenesis; Major histocompatibility complex; Human leukocyte antigen; Computational biology; Cell biology; Gene; Genetics; Gene expression; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005880059,0.0002664502,0.0003337323,0.0001148763,0.0003114093,0.00003213774,0.0003071294,0.0003160148,0.00123245],"category_scores_gemma":[0.0002193608,0.0002515086,0.0001736457,0.0001183468,0.0001185761,0.0002589988,0.00006301535,0.0003221314,0.0006158432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003817796,"about_ca_system_score_gemma":0.00007141823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002219671,"about_ca_topic_score_gemma":0.0000286771,"domain_scores_codex":[0.9975936,0.0009459366,0.0004251145,0.0002567813,0.00006352335,0.0007150293],"domain_scores_gemma":[0.9990625,0.0003329633,0.0001644642,0.0003489924,0.0000557168,0.00003540924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003195877,0.001180775,0.02338643,0.000004223133,0.001386783,0.00000231231,0.002936313,1.613079e-7,0.966059,0.00002789272,0.0003361172,0.001484118],"study_design_scores_gemma":[0.005122984,0.0002346052,0.318056,0.00005905083,0.0002114762,0.00001107345,0.0002825366,1.348644e-7,0.6561612,0.00003148043,0.019571,0.0002584383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848952,0.01327288,0.00003854927,0.00007096803,0.0008114604,0.0002503687,0.0001109076,0.0001447255,0.0004048847],"genre_scores_gemma":[0.995593,0.0002008591,0.0001217185,0.0001615408,0.00003693036,0.00003656716,0.0002219634,0.00004093329,0.003586458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3098978,"threshold_uncertainty_score":0.9999937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992307534128857,"score_gpt":0.2382862105913559,"score_spread":0.2183631352500673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}