{"id":"W2071059224","doi":"10.1016/j.bbmt.2009.06.016","title":"Sibling versus Unrelated Donor Allogeneic Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia: Refined HLA Matching Reveals More Graft-versus-Host Disease but not Less Relapse","year":2009,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Takeda Oncology; U.S. Navy; Osiris Therapeutics; Celgene; Centers for Disease Control and Prevention; Otsuka Pharmaceutical; Astellas Pharma; Therakos; Kiadis Pharma; Association of Medical Microbiology and Infectious Disease Canada; American Society for Blood and Marrow Transplantation; Teva Pharmaceutical Industries; WellPoint; HistoGenetics; CellGenix; StemCyte; Enzon Pharmaceuticals; Pfizer; Baxter International; Health Resources and Services Administration; Viropharma; Amgen; Astellas Pharma US; Bayer HealthCare; U.S. Public Health Service; U.S. Department of Defense","keywords":"Medicine; Sibling; Chronic myelogenous leukemia; Human leukocyte antigen; Graft-versus-host disease; Transplantation; Disease; Immunology; Leukemia; Hematopoietic stem cell transplantation; Hematopoietic cell; Haematopoiesis; Oncology; Internal medicine; Stem cell; Genetics; Antigen; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000651592,0.0001917276,0.0002070781,0.0003690219,0.000125807,0.0002561244,0.0001128799,0.0001268832,0.0005832838],"category_scores_gemma":[0.0006752203,0.00004881531,0.000144929,0.0003438398,0.0002060534,0.0002742253,0.0003738548,0.0001914572,0.0001136676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001585257,"about_ca_system_score_gemma":0.000139679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002949048,"about_ca_topic_score_gemma":0.000478316,"domain_scores_codex":[0.9996293,0.0001038573,0.00005190094,0.00007117871,0.0001065882,0.0000371754],"domain_scores_gemma":[0.999774,0.00004029778,0.00008025651,0.00005059157,0.00001920512,0.00003565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00411943,0.0003509602,0.5121276,0.0001878951,0.0002087465,0.0004278188,0.0002641563,0.001085663,0.3919155,0.000557708,0.0001800026,0.08857451],"study_design_scores_gemma":[0.00006397293,0.003620412,0.9316891,0.00001188309,0.000165112,0.003621329,0.0001025085,0.002606812,0.05528527,0.0003905118,0.002427139,0.00001597916],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990174,0.000212917,0.0005110803,0.000006700547,0.000002367086,0.00001174644,0.00003430037,0.000003669216,0.0001998209],"genre_scores_gemma":[0.9988267,0.0001233257,0.0007370309,0.00001830857,0.000005213933,0.000005955078,0.0002074763,0.000002273242,0.00007375006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000651592,"threshold_uncertainty_score":0.003446043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02190773798011079,"score_gpt":0.2706638552897641,"score_spread":0.2487561173096533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}