{"id":"W2071059224","doi":"10.1016/j.bbmt.2009.06.016","title":"Sibling versus Unrelated Donor Allogeneic Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia: Refined HLA Matching Reveals More Graft-versus-Host Disease but not Less Relapse","year":2009,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Takeda Oncology; U.S. Navy; Osiris Therapeutics; Celgene; Centers for Disease Control and Prevention; Otsuka Pharmaceutical; Astellas Pharma; Therakos; Kiadis Pharma; Association of Medical Microbiology and Infectious Disease Canada; American Society for Blood and Marrow Transplantation; Teva Pharmaceutical Industries; WellPoint; HistoGenetics; CellGenix; StemCyte; Enzon Pharmaceuticals; Pfizer; Baxter International; Health Resources and Services Administration; Viropharma; Amgen; Astellas Pharma US; Bayer HealthCare; U.S. Public Health Service; U.S. Department of Defense","keywords":"Medicine; Sibling; Chronic myelogenous leukemia; Human leukocyte antigen; Graft-versus-host disease; Transplantation; Disease; Immunology; Leukemia; Hematopoietic stem cell transplantation; Hematopoietic cell; Haematopoiesis; Oncology; Internal medicine; Stem cell; Genetics; Antigen; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004202782,0.0004541852,0.0007231876,0.0003399616,0.0002324213,0.00002071993,0.0001469342,0.0004821394,0.00001545272],"category_scores_gemma":[0.00002972237,0.0004407341,0.0002318249,0.0002590927,0.0001745199,0.0001688911,0.000005260321,0.00027917,0.000004441795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009644761,"about_ca_system_score_gemma":0.0003114257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007962566,"about_ca_topic_score_gemma":0.00007045089,"domain_scores_codex":[0.9974176,0.0001447615,0.0009265144,0.0007075838,0.0002601295,0.0005434428],"domain_scores_gemma":[0.9982705,0.0006380259,0.0003462856,0.0003006148,0.0001587077,0.0002858365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02034741,0.0002273586,0.001605581,0.005145023,0.000276655,0.0001769417,0.002291274,0.0001901677,0.9674684,0.0009920781,0.000007936371,0.001271107],"study_design_scores_gemma":[0.07301739,0.006286404,0.06129213,0.002366582,0.01445725,0.0007199838,0.001109184,0.0003526698,0.8380531,0.0009333664,0.00004891824,0.00136304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863995,0.001909019,0.008221968,0.00072762,0.0004087457,0.001436558,0.0005737731,0.0001427243,0.0001800841],"genre_scores_gemma":[0.9861218,0.007394651,0.003044084,0.0001829878,0.0001319107,0.00008913954,0.002907949,0.00005189085,0.00007562745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1294154,"threshold_uncertainty_score":0.9998044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02190773798011079,"score_gpt":0.2706638552897641,"score_spread":0.2487561173096533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}