{"id":"W2071063588","doi":"10.1016/j.talanta.2007.06.009","title":"Detection of Alzheimer's tau protein using localised surface plasmon resonance-based immunochip","year":2007,"lang":"en","type":"article","venue":"Talanta","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Surface plasmon resonance; Linker; Tau protein; Bovine serum albumin; Monoclonal antibody; Nanoparticle; Protein G; Biophysics; Nanotechnology; Antibody; Chromatography; Alzheimer's disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003114092,0.000176222,0.0002904797,0.0001231273,0.00009321826,0.000009852161,0.0000710504,0.0001032045,0.00006112225],"category_scores_gemma":[0.00003872636,0.0001516356,0.0001219835,0.0003032461,0.0001346172,0.00007275592,0.00002801502,0.0001647379,0.00003667549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001073912,"about_ca_system_score_gemma":0.0002414993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000761712,"about_ca_topic_score_gemma":0.00004168064,"domain_scores_codex":[0.9984756,0.00005432459,0.0003066199,0.0002544094,0.0004881044,0.0004209795],"domain_scores_gemma":[0.999118,0.00004850925,0.0001212973,0.0003521288,0.0001236178,0.0002363899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009520035,0.001423422,0.03330279,0.0002342963,0.004352702,0.000805156,0.0001149929,0.0001114035,0.9391342,0.00003979504,0.00005396078,0.01090726],"study_design_scores_gemma":[0.003541723,0.0005185627,0.0282392,0.0002958315,0.0004702476,0.00003372472,0.00006059958,0.00201189,0.9645845,0.00002792096,0.00007251855,0.0001433212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899184,0.008147038,0.0003461821,0.00003165346,0.00004511984,0.0008803756,0.00003469236,0.00006236446,0.0005341573],"genre_scores_gemma":[0.9994249,0.00001547665,0.0003789651,0.00002465868,0.00004614871,0.000008741047,0.00004661045,0.00003339932,0.00002112843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02545027,"threshold_uncertainty_score":0.6183522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03801658268451924,"score_gpt":0.312059565690059,"score_spread":0.2740429830055398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}