{"id":"W2071063740","doi":"10.1073/pnas.1405580111","title":"Discovery of a p53 variant that controls metastasis","year":2014,"lang":"en","type":"letter","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Computational biology; Biology; Metastasis; Genetics; Bioinformatics; Cancer research; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001297548,0.0004082379,0.0007718693,0.0003921091,0.001009392,0.001030005,0.0006548314,0.01254024,0.003740261],"category_scores_gemma":[0.007018123,0.0002776003,0.0005491354,0.0002556562,0.001130112,0.0007168951,0.0004634119,0.007068205,0.001805798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001249994,"about_ca_system_score_gemma":0.0006103712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001127474,"about_ca_topic_score_gemma":0.001508113,"domain_scores_codex":[0.9993562,0.0002071535,0.00005966738,0.0001252499,0.0001533186,0.00009837189],"domain_scores_gemma":[0.9976688,0.001662198,0.0001033664,0.0001503912,0.0002374706,0.0001777856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001837703,0.0003825193,0.01518578,0.0001698195,0.0001801223,0.04396958,0.0003288645,0.0005887262,0.01899803,0.02229953,0.7764286,0.1196307],"study_design_scores_gemma":[0.001909335,0.001815415,0.0291024,0.0003287629,0.0004554038,0.05224127,0.0007433154,0.00638117,0.02718783,0.05693141,0.8226925,0.000211232],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.03181827,0.004160574,0.001249997,0.9221601,0.02445347,0.00004719433,0.0004729978,0.000216329,0.01542111],"genre_scores_gemma":[0.3110391,0.005791383,0.001937817,0.590364,0.05266105,0.0001074949,0.0004395171,0.0001073526,0.03755226],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01254024,"threshold_uncertainty_score":0.01251239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05427068492430798,"score_gpt":0.3007298918596942,"score_spread":0.2464592069353862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}