{"id":"W2071076402","doi":"10.1016/s1096-4959(02)00105-7","title":"Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs)","year":2002,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo; Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Wisconsin Sea Grant Institute, University of Wisconsin; National Institutes of Health; National Institute of Environmental Health Sciences; Woods Hole Oceanographic Institution","keywords":"Aryl hydrocarbon receptor; Potency; Chemistry; Receptor; Toxicity; Polycyclic aromatic hydrocarbon; In vitro; Stereochemistry; Environmental chemistry; Biochemistry; Gene; Transcription factor; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611688,0.0001721587,0.0002102099,0.0002271501,0.0004378692,0.0003878629,0.0001748168,0.00035493,0.003802102],"category_scores_gemma":[0.0002567324,0.0002135599,0.0004349758,0.0002261509,0.0002538684,0.0002516549,0.0002836236,0.0003827289,0.0008360159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006548823,"about_ca_system_score_gemma":0.0002622968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004541893,"about_ca_topic_score_gemma":0.005830566,"domain_scores_codex":[0.9997686,0.00003234161,0.000005810011,0.00003702429,0.00006237481,0.00009392518],"domain_scores_gemma":[0.9998676,0.00003616399,0.0000242202,0.00001646387,0.00002340539,0.00003228238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005930213,0.00003273534,0.001723799,0.00005257555,0.00001947597,0.00005279355,0.00004939896,0.0002000814,0.9939963,0.0001562203,0.0001741248,0.002949436],"study_design_scores_gemma":[0.00004757196,0.00125079,0.1760929,0.00002265774,0.00004433395,0.0008805058,0.0003439715,0.001587329,0.8104174,0.0002817012,0.008999606,0.00003121643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954814,0.001290534,0.0009756623,0.00009164324,0.00003166094,0.000009417879,0.0001600528,0.00002566555,0.001933943],"genre_scores_gemma":[0.9891899,0.001417322,0.000801032,0.0001092874,0.00002529469,0.00001218623,0.0006748496,0.00001015607,0.007759917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004541893,"threshold_uncertainty_score":0.01271927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484037058786165,"score_gpt":0.2542369807276603,"score_spread":0.2393966101397987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}