{"id":"W2071113222","doi":"10.1097/tp.0b013e3181be6bc7","title":"Acute Cardiac Allograft Rejection by Directly Cytotoxic CD4 T Cells: Parallel Requirements for Fas and Perforin","year":2009,"lang":"en","type":"article","venue":"Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Perforin; Cytotoxic T cell; Fas ligand; T cell; Cytolysis; Immunology; Biology; CD8; T lymphocyte; Immune system; Cell biology; Apoptosis; In vitro; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000256303,0.0001957674,0.0003141796,0.00009981333,0.000140748,0.00002848921,0.00004228795,0.000120779,0.00001308147],"category_scores_gemma":[0.000005043741,0.0001776981,0.0001233478,0.0001144029,0.00003034529,0.0001960395,0.000001191467,0.0001061482,0.000004418328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003690919,"about_ca_system_score_gemma":0.00002525056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003025698,"about_ca_topic_score_gemma":0.00001076076,"domain_scores_codex":[0.9988374,0.00006365094,0.000300228,0.0003272819,0.0002179985,0.0002534849],"domain_scores_gemma":[0.9995356,0.0000988684,0.00007134424,0.0001275792,0.00005361391,0.0001129829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002625205,0.0001151965,0.006308207,0.0004321097,0.0002358259,0.00002257825,0.002260398,0.00001499593,0.9663758,0.0002664045,0.000575111,0.02076817],"study_design_scores_gemma":[0.01496431,0.002843302,0.2399556,0.0003873044,0.00396939,0.0001676063,0.0003627446,0.0006609021,0.7306015,0.0008234043,0.004451889,0.0008120161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8975049,0.0004034391,0.09851925,0.0008203949,0.00035703,0.00128512,0.0003197392,0.0001651994,0.0006249646],"genre_scores_gemma":[0.9439738,0.006418443,0.04671006,0.0005214136,0.0001425699,0.00004573622,0.001240096,0.00002955157,0.0009183291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2357742,"threshold_uncertainty_score":0.7246318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0226619981368456,"score_gpt":0.3221878894101939,"score_spread":0.2995258912733483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}