{"id":"W2071127741","doi":"10.1021/bi0359527","title":"Structure of Subtilosin A, a Cyclic Antimicrobial Peptide from <i>Bacillus subtilis</i> with Unusual Sulfur to α-Carbon Cross-Links:  Formation and Reduction of α-Thio-α-Amino Acid Derivatives<sup>,</sup>","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":201,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Stereochemistry; Peptide; Amino acid; Bacillus subtilis; Thio-; Hydrolysis; Tetrapeptide; Heteronuclear molecule; Amide; Nuclear magnetic resonance spectroscopy; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004774234,0.0002452058,0.000102589,0.0001248139,0.0001435741,0.0001311292,0.0001729359,0.0002185957,0.0004498569],"category_scores_gemma":[0.0001072298,0.0000803294,0.000167604,0.00014411,0.0001500077,0.0001145858,0.00006166542,0.0003210066,0.0001285138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002616617,"about_ca_system_score_gemma":0.0002070239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00140189,"about_ca_topic_score_gemma":0.001109106,"domain_scores_codex":[0.9999688,0.000005264388,0.000001724865,0.00001093461,0.00000712674,0.0000062049],"domain_scores_gemma":[0.999892,0.00001432288,0.0000378245,0.000005604834,0.00001886364,0.0000313951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001303443,0.00001282635,0.000377757,0.00002235029,0.000004425292,0.0001239833,0.00002551048,0.0002861162,0.9980302,0.00006637082,0.00002702967,0.00089293],"study_design_scores_gemma":[0.00002909347,0.0006367534,0.01639744,0.00001575771,0.00002984848,0.0007429847,0.00009456626,0.003979018,0.9750303,0.0001438519,0.002880252,0.00002010222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998027,0.0002628297,0.0008854268,0.0000341384,0.000004936162,0.000006821556,0.0002982048,0.00001101315,0.0004696232],"genre_scores_gemma":[0.9945299,0.0002970873,0.002341643,0.00003804045,0.000005711008,0.00001083169,0.001740214,0.00001268236,0.001023941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00140189,"threshold_uncertainty_score":0.002787471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008154512016875668,"score_gpt":0.2043313369055472,"score_spread":0.1961768248886716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}