{"id":"W2071136213","doi":"10.1038/oby.2011.144","title":"Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells","year":2011,"lang":"en","type":"article","venue":"Obesity","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Thrombosis and Atherosclerosis Research Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Unfolded protein response; Endoplasmic reticulum; Calreticulin; Internal medicine; Endocrinology; Peripheral blood mononuclear cell; Glucose-regulated protein; Medicine; Diabetes mellitus; Biology; In vitro; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000182246,0.0002685369,0.0002645383,0.0004501364,0.0001994686,0.0003065396,0.00007221625,0.0002581499,0.00145854],"category_scores_gemma":[0.0002621121,0.0001584341,0.0001605953,0.0005835946,0.00009859476,0.0001001971,0.0002356498,0.0002196143,0.0004280734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007205054,"about_ca_system_score_gemma":0.00009413907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003358175,"about_ca_topic_score_gemma":0.0003524292,"domain_scores_codex":[0.9998146,0.00004946429,0.0000305995,0.00004180545,0.00003896161,0.0000245495],"domain_scores_gemma":[0.9998479,0.00001792925,0.00006750819,0.00001481672,0.00002446529,0.00002747183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005802501,0.000324088,0.2196143,0.0004158471,0.0001384184,0.006345344,0.0006501819,0.00009694711,0.7456155,0.0001372623,0.0005205917,0.02033899],"study_design_scores_gemma":[0.0001672262,0.001429691,0.9440592,0.00005619129,0.0001846662,0.01149787,0.0006014425,0.0004041551,0.03609296,0.000213784,0.005267658,0.00002516548],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943119,0.003114784,0.0009214478,0.00008544407,0.00003404031,0.00005409506,0.0004348226,0.00001513052,0.001028411],"genre_scores_gemma":[0.9953647,0.001695703,0.0008806645,0.0001374318,0.00007524311,0.00009823637,0.0008934983,0.000006439448,0.0008481651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145854,"threshold_uncertainty_score":0.004879236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00743250915114636,"score_gpt":0.1988403369445378,"score_spread":0.1914078277933914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}