{"id":"W2071144245","doi":"10.1155/2012/439235","title":"Combination Immunotherapy with 4-1BBL and CTLA-4 Blockade for the Treatment of Prostate Cancer","year":2012,"lang":"en","type":"article","venue":"Clinical and Developmental Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Wuhan University; University of Toronto; National Natural Science Foundation of China","keywords":"Blockade; Immunotherapy; Prostate cancer; Cytotoxic T cell; Immune system; Medicine; CTLA-4; CTL*; Cancer; T cell; Cancer research; Immunology; Internal medicine; CD8; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004104452,0.0004796711,0.0008376114,0.0006002363,0.0001833234,0.0004296057,0.0005018399,0.0003797931,0.000975646],"category_scores_gemma":[0.0001654905,0.0002150581,0.0004003686,0.0003147517,0.0002620082,0.0002524093,0.0003496625,0.001130875,0.0003169445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003200644,"about_ca_system_score_gemma":0.0004319204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002928131,"about_ca_topic_score_gemma":0.0008121823,"domain_scores_codex":[0.9997109,0.00009385368,0.00001370725,0.00003131616,0.00007106026,0.0000791846],"domain_scores_gemma":[0.9999185,0.00001820045,0.00002040953,0.000009265629,0.000005875394,0.00002778903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003199501,0.004885626,0.001510043,0.0003396657,0.0002197206,0.0002174374,0.00006712869,0.00305105,0.9085536,0.0003927293,0.0004815713,0.07708196],"study_design_scores_gemma":[0.003825622,0.1072424,0.01160619,0.00008775722,0.0009672301,0.002294315,0.00008086031,0.008807752,0.8438437,0.0006354161,0.02054078,0.00006804759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820607,0.01271167,0.002769767,0.0003542179,0.0001531499,0.0001966641,0.00005841127,0.0001067758,0.00158869],"genre_scores_gemma":[0.9904771,0.004240186,0.003326791,0.0001015735,0.0001430759,0.0001122215,0.0001580694,0.00001447273,0.001426572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000975646,"threshold_uncertainty_score":0.003263831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02996660366881156,"score_gpt":0.3153980277085812,"score_spread":0.2854314240397696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}