{"id":"W2071251525","doi":"10.1016/j.plipres.2006.02.001","title":"Cholesterol and the interaction of proteins with membrane domains","year":2006,"lang":"en","type":"review","venue":"Progress in Lipid Research","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":311,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"","keywords":"Cholesterol; Transmembrane protein; Transmembrane domain; Membrane protein; Membrane; Sterol; Amino acid; Biochemistry; Chemistry; Biology; Structural motif; Peptide sequence; Cell biology; Computational biology; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001123563,0.0002687807,0.0007319564,0.0002167221,0.00008306676,0.00005991197,0.0004099863,0.000318341,0.000006233521],"category_scores_gemma":[0.00005081826,0.0001389812,0.0001344793,0.0003466443,0.001172369,0.000006303965,0.0002765861,0.0007389076,0.000001697488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002465251,"about_ca_system_score_gemma":0.0002027748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005110025,"about_ca_topic_score_gemma":0.0001175141,"domain_scores_codex":[0.9975899,0.000695014,0.000430489,0.0004833954,0.0004285853,0.0003726465],"domain_scores_gemma":[0.9989683,0.00007929559,0.0001951349,0.0005542498,0.000151078,0.00005195164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003622418,0.0001537426,0.0003919485,0.01061295,0.0001141605,0.000005764419,0.00005342516,6.390339e-7,0.0004219231,0.0001211996,0.00006468892,0.9876973],"study_design_scores_gemma":[0.00175942,0.000411221,0.00007581853,0.003936516,0.0001433922,0.000120363,0.00003581096,0.000001531285,0.007259453,0.000005410554,0.9860122,0.0002388556],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01074859,0.9853644,0.000003521455,0.00006834703,0.0001305817,0.002988871,0.00002592044,0.000006946316,0.0006627762],"genre_scores_gemma":[0.01483151,0.9825804,0.0001635025,0.000005155436,0.0006955466,0.001184026,0.0001409159,0.00005457499,0.0003443944],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9874585,"threshold_uncertainty_score":0.5667487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04433116178690618,"score_gpt":0.3949141804320429,"score_spread":0.3505830186451367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}