{"id":"W2071265021","doi":"10.1002/jbm.a.31249","title":"Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells","year":2007,"lang":"en","type":"article","venue":"Journal of Biomedical Materials Research Part A","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Transfection; Materials science; Stromal cell; Bone marrow; Gene delivery; Genetic enhancement; Cationic polymerization; Molecular biology; Biophysics; Polymer; Biochemistry; Biology; Cancer research; Gene; Polymer chemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002526934,0.000115049,0.0002668932,0.000316961,0.00007555328,0.00002760605,0.0002361277,0.0001754111,0.0001042414],"category_scores_gemma":[0.0004657703,0.00009299553,0.0001152594,0.0001599092,0.0002376076,0.000009526461,0.00007091561,0.0001223636,0.00002009357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006243166,"about_ca_system_score_gemma":0.0002361164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001489147,"about_ca_topic_score_gemma":0.000008369461,"domain_scores_codex":[0.9980862,0.0001800927,0.000563175,0.0001965766,0.0005651862,0.0004088203],"domain_scores_gemma":[0.9986919,0.0001400085,0.000188236,0.0001664904,0.0005369497,0.0002764399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003294946,0.0001806064,0.00002144874,0.00006388369,0.00007908112,0.00002265369,0.00003486976,0.000003345799,0.9888559,0.00002812856,0.004985332,0.002429835],"study_design_scores_gemma":[0.000785073,0.005869326,0.0006686791,0.000156491,0.0000151863,0.00002880727,0.0000820851,0.000002044634,0.9845384,0.00003928357,0.007727664,0.00008692028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972873,0.0001644328,0.001058159,0.0002730228,0.0006778093,0.0003748686,0.0001130138,0.000002007982,0.00004936936],"genre_scores_gemma":[0.9985556,0.0001254473,0.0002453099,0.00009501575,0.0008116153,0.0000215458,0.00004645854,0.0000120501,0.00008697195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005688719,"threshold_uncertainty_score":0.3792247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02539637399052993,"score_gpt":0.3396315996468622,"score_spread":0.3142352256563323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}