{"id":"W2071306349","doi":"10.1016/j.jneuroim.2009.02.001","title":"Lipopolysaccharide (LPS) stimulates adipokine and socs3 gene expression in mouse brain and pituitary gland in vivo, and in N-1 hypothalamic neurons in vitro","year":2009,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Nova Scotia Health Research Foundation","keywords":"In vivo; Adipokine; In vitro; Hypothalamus; Lipopolysaccharide; SOCS3; Cell biology; Endocrinology; Internal medicine; Pituitary gland; Kisspeptin; Gene expression; Gene; Biology; Chemistry; Signal transduction; Medicine; Leptin; STAT3; Hormone; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003123652,0.000187317,0.0006413119,0.0009546591,0.00002038235,0.00001445449,0.00008328447,0.0001429327,0.000007133375],"category_scores_gemma":[0.0003810064,0.0001616504,0.00003111239,0.0001819282,0.000110482,0.0002377099,0.00006528931,0.0006554304,2.603323e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002560848,"about_ca_system_score_gemma":0.00006006196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001109328,"about_ca_topic_score_gemma":0.00009850687,"domain_scores_codex":[0.9984985,0.0001980537,0.0006232172,0.0002525069,0.0001139232,0.0003137724],"domain_scores_gemma":[0.9993334,0.0002540959,0.000162962,0.0001449911,0.00002209517,0.00008245833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001823572,0.0002560608,0.1043737,0.00001933724,0.000006031222,0.0007108687,0.0005061312,0.00005611391,0.8879445,0.000003925888,0.00001969345,0.004280043],"study_design_scores_gemma":[0.01041135,0.0005791052,0.9465526,0.0001071787,0.00001709404,0.001189617,0.0001608984,0.0002838123,0.04006768,0.0003854477,0.0001181072,0.0001271366],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866523,0.009619161,0.000003199182,0.003395597,0.0001051816,0.0001954039,0.0000044165,0.000006068431,0.00001863076],"genre_scores_gemma":[0.9941697,0.004413601,0.0002448244,0.00107431,0.00004685903,0.000001823009,0.000001442892,0.00001601783,0.00003148614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8478768,"threshold_uncertainty_score":0.6591913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016147649942556,"score_gpt":0.2469522581555047,"score_spread":0.2367907816560791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}