{"id":"W2071338372","doi":"10.4061/2011/929456","title":"The History of Cystinosis: Lessons for Clinical Management","year":2011,"lang":"en","type":"article","venue":"International Journal of Nephrology","topic":"Biomedical Research and Pathophysiology","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"","keywords":"Cystinosis; Cysteamine; Medicine; Fanconi syndrome; LEAPS; Clinical trial; Stem-cell therapy; Disease; Bioinformatics; Intensive care medicine; Pediatrics; Cystine; Pathology; Internal medicine; Biology; Kidney; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008457777,0.00004727515,0.0001960563,0.0001059852,0.00001338941,0.000001292726,0.0003291449,0.00007801578,0.0001348857],"category_scores_gemma":[0.000395443,0.00002807988,0.0002008401,0.00002261921,0.0004328696,0.00002196153,0.00005687082,0.0002080934,0.000006450671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007703481,"about_ca_system_score_gemma":0.0002114851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000588428,"about_ca_topic_score_gemma":0.000002937995,"domain_scores_codex":[0.9989364,0.00008794591,0.0005141947,0.00007321811,0.0002564591,0.0001317691],"domain_scores_gemma":[0.998482,0.0004863653,0.0003002517,0.0000966585,0.0005321574,0.0001026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02438765,0.001399376,0.004548545,0.00006706061,0.003591117,0.0007341811,0.0004308142,2.832691e-7,0.01125044,0.04421058,0.5491163,0.3602637],"study_design_scores_gemma":[0.002447672,0.00244782,0.1351431,0.00004007652,0.00008873593,0.0002929207,0.00005726141,0.00004532978,0.00009993902,0.007050622,0.8522545,0.00003209946],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7290635,0.01435792,0.02204311,0.1572529,0.03349634,0.001459078,0.0000640364,0.00003599774,0.04222706],"genre_scores_gemma":[0.9813871,0.004818497,0.005885314,0.004892377,0.001110514,0.00001325391,0.000004391949,0.000009670992,0.001878908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3602316,"threshold_uncertainty_score":0.1594926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2085275838449424,"score_gpt":0.4429923417472459,"score_spread":0.2344647579023036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}