{"id":"W2071440708","doi":"10.1161/01.hyp.0000239673.80332.2f","title":"Sustained Normalization of High Blood Pressure in Spontaneously Hypertensive Rats by Implanted Hemin Pump","year":2006,"lang":"en","type":"article","venue":"Hypertension","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University; University of Saskatchewan","funders":"","keywords":"Hemin; Blood pressure; Downregulation and upregulation; Endocrinology; Internal medicine; Medicine; Heme oxygenase; Soluble guanylyl cyclase; Heme; Chemistry; Guanylate cyclase; Nitric oxide; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002669542,0.0003635531,0.0004575152,0.0002723571,0.0001468712,0.0001998872,0.0002141606,0.0002649336,0.0008493614],"category_scores_gemma":[0.0001728787,0.0001478596,0.0002268551,0.000118352,0.000391697,0.0003395565,0.0001919204,0.000802175,0.0001612708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002097127,"about_ca_system_score_gemma":0.0002443947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003442657,"about_ca_topic_score_gemma":0.0006453672,"domain_scores_codex":[0.9998274,0.0000331786,0.00001778947,0.00003691653,0.00004151354,0.00004329485],"domain_scores_gemma":[0.9997198,0.0000267401,0.0001038003,0.00004101425,0.00002149182,0.00008713143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009225958,0.0002866262,0.0002187781,0.00002229612,0.000007681266,0.00006964404,0.00002372029,0.00004033395,0.9958352,0.00007292747,0.00004036081,0.0024597],"study_design_scores_gemma":[0.0002390137,0.007738875,0.008422683,0.000008870101,0.00004223773,0.0002511951,0.00004106334,0.000963715,0.9806008,0.00007261315,0.001605451,0.00001350185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997318,0.0002306205,0.001874074,0.0000438556,0.00003594733,0.00003228123,0.0000937165,0.0000914972,0.0002800877],"genre_scores_gemma":[0.9919665,0.0005466069,0.004698118,0.00006201566,0.0000468196,0.00012158,0.0003149037,0.00003775521,0.002205729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008493614,"threshold_uncertainty_score":0.002841413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003547607975285493,"score_gpt":0.182091537075286,"score_spread":0.1785439291000005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}