{"id":"W2071469692","doi":"10.1074/jbc.m500028200","title":"CSX/Nkx2.5 Modulates Differentiation of Skeletal Myoblasts and Promotes Differentiation into Neuronal Cells in Vitro","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"Hospital for Sick Children; Sick Kids Foundation","keywords":"Myogenesis; C2C12; Myocyte; Cellular differentiation; Transcription factor; Cardiac myocyte; Cell biology; Biology; GATA4; Skeletal muscle; Endocrinology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001884457,0.0003290793,0.000352527,0.0002289555,0.000258017,0.0003283641,0.0002147995,0.0002808518,0.001651373],"category_scores_gemma":[0.00009399511,0.000157778,0.0003377915,0.0002293107,0.0001808737,0.0001997074,0.0003203175,0.0005302337,0.0005318756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004172274,"about_ca_system_score_gemma":0.0003702535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004295348,"about_ca_topic_score_gemma":0.01130753,"domain_scores_codex":[0.9997209,0.00003618974,0.00004565485,0.00005477443,0.00007414819,0.0000683521],"domain_scores_gemma":[0.9999489,0.000007848743,0.000006920403,0.000005893261,0.00001291429,0.00001757493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073487,0.00002503809,0.0004094129,0.00009039249,0.000008985338,0.00004910971,0.0000306051,0.0000640793,0.9976326,0.00005256998,0.00009344499,0.001436204],"study_design_scores_gemma":[0.000031034,0.0002422871,0.0181374,0.00002864569,0.00004206278,0.0001804307,0.0001043745,0.0009273543,0.9730629,0.00002642062,0.007208288,0.000008689114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790024,0.01017255,0.002628702,0.0001230178,0.00009844924,0.00006888298,0.0009927776,0.000053563,0.006859602],"genre_scores_gemma":[0.9792102,0.004676774,0.003392694,0.0001374797,0.0000219664,0.0001007351,0.002761879,0.00002660613,0.009671781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004295348,"threshold_uncertainty_score":0.00854069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068676357761687,"score_gpt":0.2543846209130871,"score_spread":0.2436978573354703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}