{"id":"W2071500438","doi":"10.1074/jbc.m604753200","title":"Helix Packing of the Cardiac Na+-Ca2+ Exchanger","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Intracellular; Cysteine; Transmembrane domain; Transmembrane protein; Biology; Cell biology; Contractility; Mutant; Biophysics; Sodium-calcium exchanger; Helix (gastropod); Biochemistry; Membrane; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006380985,0.0001383523,0.0001276285,0.0001035082,0.0002330872,0.000246773,0.0001590539,0.0002105102,0.00113105],"category_scores_gemma":[0.0001350921,0.0001182425,0.0001398082,0.00009157841,0.000133222,0.0002862088,0.0001221551,0.0002805788,0.0003263611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001829806,"about_ca_system_score_gemma":0.00008735235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002735563,"about_ca_topic_score_gemma":0.0002645242,"domain_scores_codex":[0.9999617,0.000006888767,0.000002257744,0.00001316419,0.000009279721,0.000006649675],"domain_scores_gemma":[0.9999269,0.00001056606,0.00002697394,0.000006172304,0.00001110447,0.0000182781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004860723,0.00004529786,0.00313537,0.00009693264,0.00001972699,0.0003622531,0.0001106224,0.005796034,0.9838827,0.001576538,0.0002381928,0.004250451],"study_design_scores_gemma":[0.0001702642,0.001434816,0.08136899,0.00006798664,0.0001366685,0.002108499,0.0004937586,0.163771,0.7285693,0.006580398,0.01521019,0.00008813055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949816,0.0003563064,0.003422174,0.00004902112,0.00001442329,0.000006131051,0.00004521941,0.00004630254,0.001078939],"genre_scores_gemma":[0.9974892,0.0001672177,0.001734521,0.00001787177,0.00000523166,0.000003797379,0.0001363959,0.000003412152,0.0004423027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00113105,"threshold_uncertainty_score":0.003783762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109403854790444,"score_gpt":0.2287017261278983,"score_spread":0.2177613406488539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}