{"id":"W2071522098","doi":"10.1111/xen.12115","title":"A review of piscine islet xenotransplantation using wild‐type tilapia donors and the production of transgenic tilapia expressing a “humanized” tilapia insulin","year":2014,"lang":"en","type":"review","venue":"Xenotransplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Calgary Laboratory Services; University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Tilapia; Xenotransplantation; Islet; Biology; Transplantation; Transgene; Heterologous; Glucose homeostasis; Insulin; Cell biology; Internal medicine; Endocrinology; Fish <Actinopterygii>; Fishery; Biochemistry; Medicine; Insulin resistance; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004606221,0.0007479165,0.0009161587,0.002183178,0.0002170888,0.0009112079,0.0006024557,0.0005921205,0.002220877],"category_scores_gemma":[0.0003417069,0.0003213045,0.0005653277,0.002722726,0.0003583034,0.001277002,0.0004666261,0.001014574,0.001237442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004616719,"about_ca_system_score_gemma":0.0005522246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006945914,"about_ca_topic_score_gemma":0.0008915735,"domain_scores_codex":[0.9998355,0.00001931317,0.00005109182,0.00003408923,0.00004595671,0.00001397701],"domain_scores_gemma":[0.9997836,0.00008822426,0.00004787858,0.00001008259,0.00004263924,0.00002749601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000238397,0.000135354,0.0004816495,0.02315384,0.0001327327,0.0008544496,0.0001224756,0.0004932295,0.03006636,0.002932906,0.03405372,0.9073348],"study_design_scores_gemma":[0.00001372679,0.0002538741,0.001794052,0.001560627,0.0001710124,0.002175334,0.00004742439,0.0001285938,0.004845175,0.0005664458,0.9884112,0.00003258259],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001664177,0.9920899,0.001665712,0.0003668811,0.0008199162,0.00002049309,0.0001174827,0.00005642937,0.003199064],"genre_scores_gemma":[0.002963319,0.992803,0.001300536,0.0005828191,0.0004028328,0.00002971982,0.0002415452,0.00001456741,0.00166159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002220877,"threshold_uncertainty_score":0.00742954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04811036195170573,"score_gpt":0.3301707072457893,"score_spread":0.2820603452940835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}