{"id":"W2071649098","doi":"10.1074/jbc.m113.499715","title":"Identification of Amino Acids Conferring Chain Length Substrate Specificities on Fatty Alcohol-forming Reductases FAR5 and FAR8 from Arabidopsis thaliana","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Plant Surface Properties and Treatments","field":"Agricultural and Biological Sciences","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; European Commission","keywords":"Biochemistry; Amino acid; Yeast; Biology; Fatty acid; Alanine; Saccharomyces cerevisiae; Valine; Arabidopsis thaliana; Coenzyme A; Acyl-CoA; Enzyme; Mutant; Reductase; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145915,0.0003520754,0.0002412418,0.0002219761,0.0000923289,0.0002035692,0.0002496523,0.0002207132,0.00056713],"category_scores_gemma":[0.0001318491,0.0001683783,0.0003139874,0.000177006,0.000145181,0.0001512786,0.0001800864,0.0003413191,0.0003885775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003820147,"about_ca_system_score_gemma":0.0001778026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001379479,"about_ca_topic_score_gemma":0.001572703,"domain_scores_codex":[0.9999052,0.00001247657,0.0000130247,0.00002255276,0.00002802152,0.00001877237],"domain_scores_gemma":[0.9998608,0.00002578027,0.0000438564,0.00001381316,0.00002201973,0.00003370013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003313006,0.000005179197,0.0001848352,0.00001246659,0.000001923889,0.00002622471,0.000007890466,0.00002304236,0.9993267,0.00001625732,0.000005173071,0.0003572951],"study_design_scores_gemma":[0.0000172656,0.0001642357,0.01865733,0.000007619958,0.00003808722,0.0005304496,0.00007228015,0.0007709052,0.9772831,0.00004813826,0.002394927,0.00001563132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967034,0.000509224,0.001560752,0.00005212556,0.000008958395,0.00001665458,0.0005993231,0.00003993787,0.0005096075],"genre_scores_gemma":[0.9905963,0.000406946,0.00445461,0.00007298557,0.000007202607,0.00002115868,0.002900599,0.00004461076,0.001495553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001379479,"threshold_uncertainty_score":0.002771795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04943541488243008,"score_gpt":0.2242931440418788,"score_spread":0.1748577291594487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}