{"id":"W2071656342","doi":"10.1385/nmm:3:2:105","title":"Decrease in Glial Glutamate Transporter Variants and Excitatory Amino Acid Receptor Down-Regulation in a Murine Model of ALS-PDC","year":2003,"lang":"en","type":"article","venue":"NeuroMolecular Medicine","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Medical Research and Materiel Command; Natural Sciences and Engineering Research Council of Canada; Scottish Rite Charitable Foundation of Canada; ALS Association","keywords":"Glutamate receptor; Biology; Excitotoxicity; Neuroscience; NMDA receptor; Internal medicine; Endocrinology; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003028689,0.001042275,0.0007088954,0.002251087,0.0006130738,0.0005287245,0.0005460419,0.001635124,0.002617816],"category_scores_gemma":[0.0004008877,0.0004516592,0.0004917399,0.0005403081,0.000961983,0.0006217418,0.0003135226,0.001534534,0.0005334048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007513365,"about_ca_system_score_gemma":0.0004052437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001624799,"about_ca_topic_score_gemma":0.001997141,"domain_scores_codex":[0.999639,0.00005262299,0.00004995942,0.0001053985,0.00008925727,0.00006369113],"domain_scores_gemma":[0.9991103,0.0001377867,0.0003244426,0.00007049933,0.00009572075,0.0002612206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0010343,0.0002805816,0.0005439206,0.00005562103,0.00003402692,0.0008046149,0.00004685757,0.0002384642,0.995564,0.000372155,0.0001464302,0.0008790458],"study_design_scores_gemma":[0.0002514949,0.001729321,0.01165948,0.00002554248,0.0001538179,0.003568263,0.0001251541,0.003483052,0.9761228,0.0003602866,0.00248752,0.00003333742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928197,0.0009919058,0.002562947,0.0003096644,0.00007114524,0.00006202416,0.001604329,0.0003076408,0.001270636],"genre_scores_gemma":[0.989629,0.0006164734,0.003016516,0.0001418573,0.00003740486,0.0001100065,0.001055256,0.0001513762,0.005242181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002617816,"threshold_uncertainty_score":0.008757412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01347024449142478,"score_gpt":0.2282234645204698,"score_spread":0.214753220029045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}