{"id":"W2071683944","doi":"10.1371/journal.pone.0038441","title":"Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation","keywords":"FYN; Adherens junction; Cell biology; Internalization; Cadherin; Biology; Proto-oncogene tyrosine-protein kinase Src; Molecular biology; Kinase; Chemistry; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220426,0.0001756046,0.0002962009,0.0000356458,0.0001166123,0.00001689235,0.0002055599,0.00008746692,0.0007007213],"category_scores_gemma":[0.0002485365,0.0001465258,0.00005821268,0.0001230749,0.0001074816,0.0002262698,0.0001681212,0.0001863455,0.0002722415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003040717,"about_ca_system_score_gemma":0.0000130019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001995084,"about_ca_topic_score_gemma":6.363036e-7,"domain_scores_codex":[0.9984946,0.0001076347,0.0002768491,0.0003091434,0.0004817793,0.0003299627],"domain_scores_gemma":[0.999218,0.0001026017,0.0001457774,0.0003326138,0.00007487176,0.0001261048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001945607,0.0004088032,0.001087434,0.00004196326,0.00002303619,6.302508e-7,0.0009807205,3.31077e-7,0.9922072,0.00001922999,0.004887721,0.0001483544],"study_design_scores_gemma":[0.000407719,0.0001693963,0.0004635265,0.00006860457,0.00003813224,0.00000128653,0.00008753028,0.0000130459,0.9967784,0.00003402188,0.001783661,0.0001546932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950268,0.0003080019,0.0000494754,0.0002003727,0.0005311683,0.0002044303,0.0001024975,0.00007867769,0.003498554],"genre_scores_gemma":[0.9938214,0.0001175602,0.000287596,0.0002688367,0.0001994188,0.00001405983,0.000001925935,0.00002524725,0.005263899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004571168,"threshold_uncertainty_score":0.7672406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06262826954996269,"score_gpt":0.2521516692971181,"score_spread":0.1895233997471554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}