{"id":"W2071692019","doi":"10.1159/000335850","title":"Curcumin Blocks Kv11.1 (&lt;i&gt;erg&lt;/i&gt;) Potassium Current and Slows Proliferation in the Infant Acute Monocytic Leukemia Cell line THP-1","year":2011,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"THP1 cell line; Cell growth; Curcumin; Myeloid leukemia; Cell culture; Leukemia; Potassium channel; Cell biology; Monocytic leukemia; Haematopoiesis; Intracellular; Cancer research; Chemistry; Stem cell; Biology; Medicine; Pharmacology; Immunology; Internal medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002397728,0.0003391952,0.0002749599,0.00004579669,0.0001718272,0.00002447478,0.0003719274,0.000456145,0.00002871855],"category_scores_gemma":[0.00003504699,0.0002617111,0.00008953206,0.0001704743,0.0005675628,0.000008707504,0.0002655817,0.0003233109,0.000008190005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003024089,"about_ca_system_score_gemma":0.0001535551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008323559,"about_ca_topic_score_gemma":0.000009369476,"domain_scores_codex":[0.9982338,0.00008719487,0.0003861958,0.0007507364,0.0001365403,0.000405565],"domain_scores_gemma":[0.9989648,0.00002927805,0.0001593125,0.0006233463,0.00006823667,0.000154965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009301752,0.0002210461,0.0002868274,0.0001004746,0.00003910645,0.000006798254,0.0001920656,0.000001680424,0.9969922,0.00008691601,0.001059821,0.0009200844],"study_design_scores_gemma":[0.0008090715,0.0001777653,0.002377133,0.00001963331,0.00009180776,0.00004427396,0.00004408427,0.0003973778,0.9816678,0.0004323351,0.01359241,0.0003463386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993028,0.005192861,0.0005093002,0.0002033453,0.00009481901,0.0004079518,0.0000631062,0.00001982489,0.0004807311],"genre_scores_gemma":[0.9968719,0.0009262749,0.0002067169,0.0002122156,0.000368701,0.0001898494,0.0008918272,0.00002237612,0.0003101482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01532439,"threshold_uncertainty_score":0.9999835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009969647844947277,"score_gpt":0.224889398078345,"score_spread":0.2149197502333977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}