{"id":"W2071705919","doi":"10.1021/bi050195t","title":"Characterization of <i>Caenorhabditis elegans</i> Exonuclease-3 and Evidence That a Mg<sup>2+</sup>-Dependent Variant Exhibits a Distinct Mode of Action on Damaged DNA","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"AP site; Exonuclease; Caenorhabditis elegans; Endonuclease; AP endonuclease; DNA; Biology; Biochemistry; Molecular biology; Chemistry; DNA polymerase; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656606,0.0002332275,0.0002328279,0.00003886259,0.00005631683,0.00002003672,0.0001995833,0.0002471861,0.00003307139],"category_scores_gemma":[0.0001829662,0.0002427227,0.00009044593,0.00007807981,0.00008937215,0.00001964509,0.0001256781,0.0001093176,0.000003242722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003782359,"about_ca_system_score_gemma":0.00008470151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000195179,"about_ca_topic_score_gemma":0.000006469234,"domain_scores_codex":[0.9986179,0.00005765056,0.0003202055,0.0005082706,0.0002791568,0.000216746],"domain_scores_gemma":[0.9988709,0.00002330108,0.00034704,0.0005470393,0.0001003199,0.000111409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002496074,0.0001627688,0.0003131161,0.0002159468,0.00004279754,0.000005431642,0.00006656047,0.00003262452,0.9960924,0.00001555503,0.0000666182,0.002736616],"study_design_scores_gemma":[0.0005074167,0.0002050072,0.0008796562,0.0002330872,0.00004680779,0.00005579743,0.00006410228,0.0008309761,0.9966421,0.000009824804,0.0003027337,0.0002224553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977175,0.0001766542,0.001368545,0.0001033165,0.00004146135,0.00020927,0.0001649664,0.00002441941,0.0001938699],"genre_scores_gemma":[0.9982018,0.0002312827,0.000488,0.0000846184,0.0002016557,0.00002452333,0.000238396,0.00003391939,0.0004958022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00251416,"threshold_uncertainty_score":0.9897943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530547331065643,"score_gpt":0.2423968505085047,"score_spread":0.2270913771978483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}