{"id":"W2071728326","doi":"10.1016/s0969-8051(01)00193-7","title":"Radiosynthesis and in vivo evaluation of the pseudopeptide δ-opioid antagonist [125I]-ITIPP(ψ)","year":2001,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Radiosynthesis; Tetrapeptide; Chemistry; In vivo; Antagonist; Desmethyl; Metabolite; Biodistribution; Opioid; Stereochemistry; Receptor; Opioid receptor; Opioid antagonist; Pharmacology; In vitro; Biochemistry; (+)-Naloxone; Medicine; Biology; Peptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005892456,0.0006132699,0.0004360891,0.0003209013,0.0004214539,0.0005003079,0.0007243258,0.0005845307,0.001756587],"category_scores_gemma":[0.0003816115,0.0005295787,0.0002677602,0.0002841203,0.000401494,0.0004413802,0.0001823292,0.001384371,0.0006563403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004407987,"about_ca_system_score_gemma":0.000714059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003315938,"about_ca_topic_score_gemma":0.002760238,"domain_scores_codex":[0.999795,0.00006711562,0.000008047859,0.00003564633,0.00002954475,0.00006454422],"domain_scores_gemma":[0.9998006,0.0000565002,0.00004681932,0.00002884229,0.00002234983,0.00004485282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003691889,0.0005267842,0.000195582,0.00007047423,0.00003171722,0.0001025826,0.00006861635,0.0007282372,0.9906232,0.0003997199,0.0001728188,0.003388276],"study_design_scores_gemma":[0.0003654722,0.0072734,0.001517748,0.00001149848,0.0001151186,0.0005511972,0.0001073302,0.002681913,0.9850737,0.00008909163,0.00219472,0.00001893175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843985,0.002346681,0.00852324,0.0001654684,0.00006693068,0.0001807249,0.0003211475,0.0001320506,0.003865308],"genre_scores_gemma":[0.9864167,0.001940889,0.005165287,0.0001445899,0.00003344457,0.0001665219,0.0007481506,0.0001081671,0.005276243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003315938,"threshold_uncertainty_score":0.006593227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08146171125891527,"score_gpt":0.3674369488109177,"score_spread":0.2859752375520024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}