{"id":"W2071760228","doi":"10.1111/j.1526-4610.2005.05004.x","title":"Zolmitriptan 5 mg Nasal Spray: Efficacy and Onset of Action in the Acute Treatment of Migraine—Results From Phase 1 of the REALIZE Study","year":2004,"lang":"en","type":"article","venue":"Headache The Journal of Head and Face Pain","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Zolmitriptan; Migraine; Nasal spray; Medicine; Onset of action; Action (physics); Phase (matter); Pharmacology; Anesthesia; Nasal administration; Internal medicine; Sumatriptan; Chemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002396126,0.0001849987,0.0006674457,0.00009244274,0.000100333,0.000005966765,0.000129014,0.00006040331,0.0000042106],"category_scores_gemma":[0.000360657,0.00007897366,0.0001560679,0.0002327909,0.0002290782,0.00004509695,0.00002863609,0.0002587443,1.348487e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004809136,"about_ca_system_score_gemma":0.0001328639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002779019,"about_ca_topic_score_gemma":0.002783193,"domain_scores_codex":[0.9977694,0.000730459,0.000811521,0.0001234479,0.0003957163,0.0001695002],"domain_scores_gemma":[0.9979375,0.001035261,0.0005430671,0.0003224706,0.0001008724,0.00006081694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"qualitative","study_design_gemma":"observational","study_design_scores_codex":[0.05620008,0.02987997,0.1383807,0.0004257688,0.004901609,0.0002820017,0.5569073,0.0001582905,0.1705159,0.00008081753,0.01256005,0.02970752],"study_design_scores_gemma":[0.07839381,0.03181248,0.7204108,0.001357039,0.003080104,0.0005876439,0.1411725,0.0001337378,0.0184219,0.000456751,0.003904524,0.0002687333],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857309,0.004713087,0.00003800631,0.008626084,0.00001721171,0.0007059498,0.0001173905,0.000002731083,0.00004859852],"genre_scores_gemma":[0.9973766,0.002201314,0.0001096299,0.0001510978,0.00007392521,0.000003368099,0.000005356351,0.000008427405,0.0000702783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5820301,"threshold_uncertainty_score":0.4201064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06777463072592138,"score_gpt":0.3732353311938971,"score_spread":0.3054607004679757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}