{"id":"W2071815394","doi":"10.1371/journal.pone.0018724","title":"Temperature-Induced Protein Secretion by Leishmania mexicana Modulates Macrophage Signalling and Function","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; McGill University Health Centre; McMaster University; McGill University","keywords":"Leishmania mexicana; Biology; Cell biology; Secretion; Leishmania; Macrophage; Phagocytosis; Biochemistry; Parasite hosting; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002542601,0.0001870107,0.0003475941,0.000110231,0.0001764949,0.00003469125,0.00006713595,0.0001301878,0.0002625759],"category_scores_gemma":[0.0001806404,0.0001620312,0.00004092281,0.0001815699,0.00007553965,0.0001712088,0.00006361402,0.0003689401,0.00004554601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007448361,"about_ca_system_score_gemma":0.00003516426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002518454,"about_ca_topic_score_gemma":0.00002029745,"domain_scores_codex":[0.9984661,0.00007205421,0.0002249726,0.0003809687,0.0005233746,0.0003324902],"domain_scores_gemma":[0.9992659,0.00002646866,0.00006831715,0.0002212279,0.000226409,0.0001916859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003618949,0.0006743533,0.00360289,0.0002601278,0.0004140969,0.00002457988,0.0003235685,8.149559e-8,0.9934989,0.00007536312,0.0002104762,0.0005536829],"study_design_scores_gemma":[0.001138228,0.001182091,0.03510734,0.0004452539,0.0002281666,0.000005753791,0.0002436933,0.0004917279,0.9606109,0.0003146619,0.00002633414,0.0002058245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995446,0.0009536354,0.0000371041,0.0004650227,0.00001751836,0.001023602,0.000008016205,0.0001252572,0.001923895],"genre_scores_gemma":[0.9970695,0.0001681317,0.001076636,0.0001196513,0.0001355908,0.0001383617,0.00002910287,0.00004010909,0.001222965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03288797,"threshold_uncertainty_score":0.6607441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06014636288102986,"score_gpt":0.2472406392391094,"score_spread":0.1870942763580795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}