{"id":"W2071822677","doi":"10.1371/journal.pone.0054621","title":"The Immunosuppressive Agent Mizoribine Monophosphate Is an Inhibitor of the Human RNA Capping Enzyme","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Mizoribine; Enzyme; Chemistry; RNA; Biochemistry; Biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005485858,0.00009055436,0.00008936638,0.000009249195,0.0001873656,0.00003408222,0.0002346701,0.00005507982,0.00008991888],"category_scores_gemma":[0.00003779936,0.00005578141,0.00007031606,0.00004364358,0.00009181982,0.000006056568,0.0001081405,0.00004709386,0.00001392908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007574381,"about_ca_system_score_gemma":0.0000270404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005748665,"about_ca_topic_score_gemma":0.000005715402,"domain_scores_codex":[0.9993181,0.00005047914,0.0001762654,0.0001552064,0.0001610153,0.0001388991],"domain_scores_gemma":[0.999172,0.000006174549,0.0001171545,0.00050622,0.0001310075,0.00006738403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000157902,0.0002314976,0.001242269,0.00001203697,0.00008787516,1.816193e-7,0.0001139432,0.000007269274,0.9960834,0.00005465284,0.001949937,0.0002011603],"study_design_scores_gemma":[0.0003614627,0.00006969721,0.01627449,0.00002897226,0.00003489162,2.238421e-7,0.0001049093,0.0002125773,0.9820396,0.0001382364,0.0006514185,0.00008356322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974288,0.001167527,0.000008530769,0.0006145459,0.00004851791,0.0002944248,0.00001354527,0.000006426391,0.0004177352],"genre_scores_gemma":[0.996699,0.00007898134,0.00005981576,0.0002963072,0.0001320181,0.00004340954,0.00002585699,0.00001247867,0.00265218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01503222,"threshold_uncertainty_score":0.22747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0220215720310017,"score_gpt":0.2257322054631035,"score_spread":0.2037106334321018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}