{"id":"W2071842134","doi":"10.1021/bm060940x","title":"Palmitic Acid-Modified Poly-<scp>l</scp>-Lysine for Non-Viral Delivery of Plasmid DNA to Skin Fibroblasts","year":2007,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lipofectamine; Plasmid; Molecular biology; Green fluorescent protein; Polylysine; Gene delivery; DNA; Chemistry; Transfection; Palmitic acid; In vitro; Biology; Biochemistry; Recombinant DNA; Gene; Fatty acid; Vector (molecular biology)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003073604,0.0004843031,0.0002531081,0.0001839068,0.0001440286,0.000290313,0.0002167893,0.0003781983,0.0006013156],"category_scores_gemma":[0.0003194164,0.000191287,0.0003026472,0.0001918525,0.0002243214,0.0003378936,0.0001912004,0.0002530845,0.0004622082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003534791,"about_ca_system_score_gemma":0.0002853487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005043379,"about_ca_topic_score_gemma":0.0007779574,"domain_scores_codex":[0.9997886,0.00005631425,0.00002360211,0.00004418091,0.00005900018,0.00002832942],"domain_scores_gemma":[0.9997713,0.00005654307,0.00007938174,0.00002316015,0.00003222206,0.00003745254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003363917,0.000006913388,0.0000567335,0.00002852963,0.000003442274,0.00002581565,0.000005108114,0.00007169763,0.9989647,0.00002567384,0.000007977175,0.000769921],"study_design_scores_gemma":[0.000006033988,0.00009034558,0.0003638863,0.000001857283,0.000006497491,0.00009887674,0.000003129099,0.0002605015,0.9984365,0.000008178004,0.0007214764,0.000002690233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658567,0.003003011,0.02892853,0.00008222956,0.00005575009,0.0001445157,0.000209065,0.0001261616,0.001594096],"genre_scores_gemma":[0.975367,0.001807454,0.01942048,0.00006905031,0.00001556588,0.00008514264,0.0003614001,0.00004287321,0.002830972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006013156,"threshold_uncertainty_score":0.002564728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009111798532349757,"score_gpt":0.2531238923340635,"score_spread":0.2440120938017137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}