{"id":"W2071918153","doi":"10.1371/journal.pbio.0020130","title":"Pax7 Is Necessary and Sufficient for the Myogenic Specification of CD45+:Sca1+ Stem Cells from Injured Muscle","year":2004,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Muscular Dystrophy Association; Howard Hughes Medical Institute","keywords":"MYF5; MyoD; Myogenesis; Myogenin; Biology; Myocyte; Myogenic regulatory factors; Cell biology; Skeletal muscle; Myosin; Stem cell; MyoD Protein; Mef2; Immunology; Transcription factor; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000149712,0.0002709845,0.0002931936,0.0003222309,0.0002029436,0.0004344197,0.0002778304,0.0003721352,0.003028506],"category_scores_gemma":[0.0002702013,0.0003452488,0.0001938956,0.0001457026,0.0003552003,0.000290904,0.0004143378,0.0004630145,0.001210798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002903457,"about_ca_system_score_gemma":0.0003644905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004142004,"about_ca_topic_score_gemma":0.001053013,"domain_scores_codex":[0.9997059,0.00004143062,0.00002945648,0.00004310528,0.0001052988,0.000074845],"domain_scores_gemma":[0.9996223,0.00008038097,0.00009108974,0.00004832916,0.00003759036,0.0001202926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004132182,0.00001382,0.0003553966,0.00002657356,0.000004225454,0.00008358333,0.000009232568,0.00003062156,0.9985879,0.0001355354,0.00003323282,0.0006785887],"study_design_scores_gemma":[0.00002523949,0.0002059397,0.01276536,0.00001426517,0.00002028814,0.0009147062,0.000084751,0.001149242,0.9806831,0.0001706622,0.003961041,0.000005340911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920758,0.00149159,0.002637407,0.0001218991,0.00003524935,0.00002744594,0.0003470801,0.0001383303,0.003125142],"genre_scores_gemma":[0.9922914,0.000566919,0.001706105,0.00004266196,0.00001367238,0.00004442722,0.001206257,0.00007099449,0.004057578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003028506,"threshold_uncertainty_score":0.01013136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859191794161295,"score_gpt":0.2389276024753509,"score_spread":0.2203356845337379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}