{"id":"W2072152122","doi":"10.1038/sj.onc.1207940","title":"Genetic programs regulating HSC specification, maintenance and expansion","year":2004,"lang":"en","type":"review","venue":"Oncogene","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Stem cell; Haematopoiesis; Induced pluripotent stem cell; Chromatin; Cell biology; Population; Immunology; Genetics; Embryonic stem cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007831223,0.001306146,0.001566819,0.001614738,0.000432338,0.001460027,0.001498409,0.001535911,0.001711438],"category_scores_gemma":[0.0007019186,0.0004013743,0.0002831109,0.001983211,0.00138814,0.001327636,0.0006321999,0.001901368,0.001473934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001180361,"about_ca_system_score_gemma":0.001115682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001319483,"about_ca_topic_score_gemma":0.002602622,"domain_scores_codex":[0.9998052,0.00002387024,0.00002611293,0.00004796458,0.00006808013,0.00002891532],"domain_scores_gemma":[0.9996504,0.0001524293,0.0000461133,0.00001776109,0.00009729285,0.00003614083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002383832,0.00006775797,0.0005966561,0.007852046,0.00007423434,0.0009311029,0.0001431314,0.001338945,0.03303821,0.02185818,0.0336747,0.9001867],"study_design_scores_gemma":[0.00003630635,0.0000508339,0.001860685,0.0008359539,0.0001011893,0.001752152,0.0001835168,0.0002261808,0.01330643,0.007058432,0.9745576,0.00003067944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008778745,0.9909971,0.002628373,0.0006650025,0.0008239184,0.00001768975,0.00009071066,0.00006696473,0.003832339],"genre_scores_gemma":[0.003619774,0.9915275,0.001506828,0.0002755601,0.0003907802,0.00002633946,0.0001340713,0.000006982252,0.002512248],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001711438,"threshold_uncertainty_score":0.008564174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03630339901445875,"score_gpt":0.3100569183328869,"score_spread":0.2737535193184282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}