{"id":"W2072194574","doi":"10.1371/journal.pone.0110055","title":"Dimerization Capacities of FGF2 Purified with or without Heparin-Affinity Chromatography","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Affinity chromatography; Heparin; Chemistry; Heteronuclear single quantum coherence spectroscopy; Chromatography; Fibroblast growth factor; Monomer; Ion chromatography; Biochemistry; Dimer; Stereochemistry; Nuclear magnetic resonance spectroscopy; Enzyme; Polymer; Receptor; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001082652,0.0001207172,0.0002045919,0.00006873768,0.0000489184,0.00001473287,0.0001536936,0.00009339224,0.0000506324],"category_scores_gemma":[0.0001187145,0.00009322824,0.00003527277,0.0001508378,0.0002492581,0.00000543069,0.00006086367,0.00008176381,0.000006825171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004644615,"about_ca_system_score_gemma":0.00005301506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004716716,"about_ca_topic_score_gemma":0.0001095405,"domain_scores_codex":[0.9990624,0.00007914728,0.0001485764,0.0002243264,0.0002859682,0.0001996439],"domain_scores_gemma":[0.9993447,0.00001965835,0.00008047069,0.0003418948,0.0001431366,0.00007013858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003612803,0.0003144067,0.0737303,0.0001878363,0.0001847596,2.975578e-7,0.00006412419,0.000003659968,0.9249677,0.00007412963,0.00005753532,0.00005395141],"study_design_scores_gemma":[0.0005158575,0.001126371,0.01149958,0.00008532831,0.00003356671,0.000001798821,0.00004502613,0.0001115795,0.9862497,0.00001952943,0.0001733165,0.0001383015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972031,0.00003124437,0.0007005276,0.00002616352,0.00000908425,0.0002179157,0.00001526532,0.00002049329,0.001776197],"genre_scores_gemma":[0.9969185,0.00002916017,0.002468102,0.00002907834,0.00006832677,0.0000299093,0.00008343213,0.00002685202,0.0003466522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06223072,"threshold_uncertainty_score":0.3801737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03164609442755763,"score_gpt":0.2304503460105858,"score_spread":0.1988042515830282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}