{"id":"W2072235312","doi":"10.1074/jbc.m807431200","title":"In Vivo Modulation of O-GlcNAc Levels Regulates Hippocampal Synaptic Plasticity through Interplay with Phosphorylation","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Drexel University; Alzheimer's Association","keywords":"Synaptic plasticity; Hippocampal formation; Phosphorylation; Neuroscience; In vivo; Modulation (music); Plasticity; Neuroplasticity; Metaplasticity; Chemistry; Cell biology; Nonsynaptic plasticity; Biology; Materials science; Biochemistry; Physics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008773017,0.0003590398,0.0003009694,0.000168466,0.0001705921,0.0003447712,0.0002274444,0.0003152583,0.001368893],"category_scores_gemma":[0.0001114413,0.0001601738,0.0003139386,0.0001500191,0.0003353821,0.000365864,0.000229524,0.000809877,0.0003004241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003032297,"about_ca_system_score_gemma":0.0001995103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004459924,"about_ca_topic_score_gemma":0.0008130306,"domain_scores_codex":[0.9999009,0.000009918097,0.000006867536,0.0000237312,0.0000156473,0.00004291416],"domain_scores_gemma":[0.9999095,0.000004914676,0.00003146999,0.000007209378,0.000008268359,0.00003859673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004806725,0.00005895973,0.0002943292,0.00005820218,0.00001290793,0.00006352333,0.00001439712,0.00003608862,0.9975199,0.00008627941,0.00006980219,0.001304933],"study_design_scores_gemma":[0.00006463206,0.000852035,0.03727962,0.00002060185,0.00006976439,0.0002598623,0.0001057444,0.00114592,0.9576573,0.0004222231,0.002107302,0.00001501177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928674,0.003279768,0.001539156,0.0002869492,0.00007789047,0.00002470084,0.0003983201,0.00008302569,0.001442944],"genre_scores_gemma":[0.9946356,0.002158907,0.0008914694,0.0001215234,0.00002653028,0.00005339255,0.0003989169,0.00002227361,0.001691257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001368893,"threshold_uncertainty_score":0.004579365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02734567221405367,"score_gpt":0.2823085435030793,"score_spread":0.2549628712890256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}