{"id":"W2072269889","doi":"10.1139/v02-068","title":"Water content influences the selectivity of CALB-catalyzed kinetic resolution of phenoxymethyl-substituted secondary alcohols","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Kinetic resolution; Water activity; Tetrahydrofuran; Cyclohexane; Organic chemistry; Catalysis; Hydrolysis; Candida antarctica; Toluene; Methanol; Acetonitrile; Solvent; Lipase; Water content; Enantioselective synthesis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002577812,0.0001020601,0.0001984968,0.00003876639,0.00005691091,0.00001213818,0.0002426595,0.000113782,0.0001884923],"category_scores_gemma":[0.0002043626,0.00006919146,0.0001298367,0.0001078718,0.0002370803,0.00001127136,0.00001608844,0.0001318881,9.214622e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003116774,"about_ca_system_score_gemma":0.0002294641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004773576,"about_ca_topic_score_gemma":0.0005763742,"domain_scores_codex":[0.9991332,0.00004057501,0.0004109825,0.0001180739,0.0001222502,0.0001748919],"domain_scores_gemma":[0.9989331,0.00001313741,0.0002801726,0.0002304865,0.0003984475,0.0001446736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001835431,0.00002003128,0.00130901,0.00004110505,0.00008458172,0.000002692068,0.0001459653,0.0002182531,0.9971275,0.000002483994,0.0006880868,0.0003419073],"study_design_scores_gemma":[0.0003970227,0.00004526214,0.002352033,0.00003490144,0.00004544689,0.00005247435,0.0001079749,0.00004143961,0.9936134,0.00001332892,0.003215763,0.00008093425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957232,0.003232965,0.0001073976,0.0001448372,0.0000619148,0.00005724437,0.00002969171,8.731411e-7,0.0006419109],"genre_scores_gemma":[0.9994974,0.00008369242,0.00003377593,0.00003873815,0.00009584511,0.000002030678,0.00005060414,0.000008177215,0.0001897867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003774185,"threshold_uncertainty_score":0.2821546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02072656739542767,"score_gpt":0.213215099294323,"score_spread":0.1924885318988953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}