{"id":"W2072271141","doi":"10.1016/j.reprotox.2014.12.005","title":"In utero exposure to the endocrine disruptor di(2-ethylhexyl) phthalate targets ovarian theca cells and steroidogenesis in the adult female rat","year":2014,"lang":"en","type":"article","venue":"Reproductive Toxicology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; F. Hoffmann-La Roche","keywords":"Phthalate; Endocrinology; Endocrine disruptor; Internal medicine; In utero; Anogenital distance; Offspring; Estrous cycle; Theca; Litter; Endocrine system; Andrology; Biology; Ovary; Chemistry; Pregnancy; Hormone; Medicine; Fetus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001043551,0.0002415426,0.0003047157,0.00005059293,0.0001326625,0.0000362288,0.0004851527,0.00006435054,0.0001406528],"category_scores_gemma":[0.0005440341,0.0001350663,0.00006265131,0.0003000521,0.0002558498,0.0001364684,0.0003877075,0.000282729,0.00009766152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007634711,"about_ca_system_score_gemma":0.000005816205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004345968,"about_ca_topic_score_gemma":0.0006187396,"domain_scores_codex":[0.9974443,0.0006308901,0.000307056,0.0008866098,0.0002039239,0.0005272654],"domain_scores_gemma":[0.9985604,0.0004397744,0.000096209,0.0008109065,0.00001537512,0.00007734911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000233232,0.000654434,0.1139546,0.00003574532,0.00003450211,0.0002052446,0.00949987,0.00229257,0.8550493,0.0003990987,0.0029862,0.01465525],"study_design_scores_gemma":[0.001874764,0.001344967,0.5155632,0.00003750322,0.00004906836,0.0003364514,0.001246192,0.0002323075,0.4323421,0.001326662,0.04498578,0.0006610212],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853849,0.0001596355,0.00002785573,0.01216681,0.0003293668,0.0008242364,0.000006692293,0.00001645935,0.001084087],"genre_scores_gemma":[0.997214,0.00004676045,0.0003265857,0.001399632,0.0002720542,0.0001738107,0.0000026862,0.00002085508,0.0005435686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4227072,"threshold_uncertainty_score":0.5507845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008702773419632671,"score_gpt":0.291885679541237,"score_spread":0.2831829061216043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}