{"id":"W2072280233","doi":"10.1016/j.biomaterials.2011.07.042","title":"A nanobiohybrid complex of recombinant baculovirus and Tat/DNA nanoparticles for delivery of Ang-1 transgene in myocardial infarction therapy","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sanofi (Canada); McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Faculty of Medicine, McGill University","keywords":"Gene delivery; Genetic enhancement; Immunogenicity; Transgene; Angiogenesis; Myocardial infarction; In vivo; Recombinant DNA; Transduction (biophysics); Biology; Molecular biology; Pharmacology; Immune system; Gene; Medicine; Immunology; Biophysics; Cardiology; Biochemistry; Cancer research; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002087023,0.0002464226,0.0002259644,0.0002421282,0.0002401732,0.000327984,0.000324524,0.000550552,0.0008823746],"category_scores_gemma":[0.0001251551,0.000254864,0.000217538,0.0001278399,0.0001867922,0.000288266,0.0002171451,0.0004219669,0.0002357639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000503009,"about_ca_system_score_gemma":0.0002169586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007995276,"about_ca_topic_score_gemma":0.001242066,"domain_scores_codex":[0.9998583,0.00001772972,0.00001027859,0.0000396483,0.0000470172,0.00002712022],"domain_scores_gemma":[0.9999477,0.00001401452,0.00001139381,0.000004396069,0.000008887404,0.00001356108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003011969,0.00001290685,0.00002685339,0.00002656728,0.000004602607,0.00002364915,0.000008285617,0.00007277036,0.9988166,0.0001850969,0.00003512869,0.0007574628],"study_design_scores_gemma":[0.0000129671,0.00006385832,0.000362535,0.000003469542,0.00002055521,0.0001332129,0.000005748356,0.001458866,0.9959289,0.00003952312,0.001964532,0.000005787742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722816,0.003776335,0.01979946,0.0003095165,0.0001244775,0.00007542211,0.000100614,0.0001880646,0.003344539],"genre_scores_gemma":[0.9871225,0.0005872915,0.008698706,0.0001080802,0.00001581399,0.00005085721,0.0001166548,0.00002653294,0.003273532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008823746,"threshold_uncertainty_score":0.003649592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05217136916288451,"score_gpt":0.2687765882669577,"score_spread":0.2166052191040732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}