{"id":"W2072280233","doi":"10.1016/j.biomaterials.2011.07.042","title":"A nanobiohybrid complex of recombinant baculovirus and Tat/DNA nanoparticles for delivery of Ang-1 transgene in myocardial infarction therapy","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sanofi (Canada); McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Faculty of Medicine, McGill University","keywords":"Gene delivery; Genetic enhancement; Immunogenicity; Transgene; Angiogenesis; Myocardial infarction; In vivo; Recombinant DNA; Transduction (biophysics); Biology; Molecular biology; Pharmacology; Immune system; Gene; Medicine; Immunology; Biophysics; Cardiology; Biochemistry; Cancer research; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526293,0.0001028301,0.0002041308,0.00004820267,0.00002843991,0.000006559582,0.00006199867,0.0000765056,0.00003821725],"category_scores_gemma":[0.00001293732,0.00008863417,0.00008090837,0.00004376029,0.00008500748,0.000005726651,0.00002691553,0.000003749055,4.716794e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003724124,"about_ca_system_score_gemma":0.00002552636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000222209,"about_ca_topic_score_gemma":0.00001869447,"domain_scores_codex":[0.9992624,0.00007672647,0.0003020704,0.000181444,0.00004752848,0.0001298617],"domain_scores_gemma":[0.9996432,0.000007442363,0.0001197189,0.0001364279,0.00005628702,0.00003693475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001140604,0.000160824,0.00160098,0.00004928191,0.0000509887,4.064155e-7,0.0001078213,8.250641e-7,0.994933,0.00002305206,0.0002959431,0.00163627],"study_design_scores_gemma":[0.001293293,0.0008710927,0.03373376,0.00002023864,0.00001192887,0.00000447604,0.00002830902,0.000002759489,0.9627707,0.000188157,0.0009729938,0.0001023004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986119,0.0005550518,0.00002705717,0.000008687386,0.0003211617,0.0003149406,0.0001290325,0.000005729756,0.0000263849],"genre_scores_gemma":[0.9988241,0.000649808,0.0003184346,0.00004074248,0.00004348809,0.00005278875,0.00005225758,0.00001233126,0.00000604399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03216231,"threshold_uncertainty_score":0.3614396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05217136916288451,"score_gpt":0.2687765882669577,"score_spread":0.2166052191040732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}